{"title":"Cerebral cortex Functional Networks of Transdermal Electrical Stimulation at Daling (PC7) Acupoint.","authors":"Haili Wang, Ning Yin, Aoxiang Wang, Guizhi Xu","doi":"10.1177/15500594221123692","DOIUrl":null,"url":null,"abstract":"<p><p>The cerebral cortex functional network of Electroencephalogram (EEG) signals during transcutaneous electrical acupoint stimulation (TEAS) on 21 healthy subjects was constructed by using three modules: standard low-resolution brain electromagnetic tomography (sLORETA), phase-locking value (<i>PLV</i>), and complex network. We investigated the brain functional network triggered by PC7 stimulation by comparing with resting state and non-acupoint stimulation. The results showed that the PC7 stimulation mainly activated frontal lobe and temporal lobe including prefrontal cortex (BA10), insular lobe (BA13), temporal gyrus (BA22), anterior cingulate cortex (BA32), temporal pole (BA38), dorsolateral prefrontal cortex (BA46), and inferior frontal cortex (BA47), which are all closely linked to cognition, spirit, and emotion in brain. Furthermore, the degrees of node in frontal, temporal, and whole brain are increased significantly or extreme significantly with <i>p</i> < 0.05, <i>p</i> < 0.05, and <i>p</i> < 0.01, respectively; clustering coefficient in frontal, temporal, and whole brain are all statistically significant (<i>p</i> < 0.05). The information transmission efficiency of cerebral cortex has been greatly improved. During PC7 stimulation, the topological changes in the activation of cerebral regions and cortical functional networks are consistent with the therapeutic effect, which may provide theoretical support for acupoint stimulation to regulate nerve function.</p>","PeriodicalId":10682,"journal":{"name":"Clinical EEG and Neuroscience","volume":"54 2","pages":"106-116"},"PeriodicalIF":1.6000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical EEG and Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/15500594221123692","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The cerebral cortex functional network of Electroencephalogram (EEG) signals during transcutaneous electrical acupoint stimulation (TEAS) on 21 healthy subjects was constructed by using three modules: standard low-resolution brain electromagnetic tomography (sLORETA), phase-locking value (PLV), and complex network. We investigated the brain functional network triggered by PC7 stimulation by comparing with resting state and non-acupoint stimulation. The results showed that the PC7 stimulation mainly activated frontal lobe and temporal lobe including prefrontal cortex (BA10), insular lobe (BA13), temporal gyrus (BA22), anterior cingulate cortex (BA32), temporal pole (BA38), dorsolateral prefrontal cortex (BA46), and inferior frontal cortex (BA47), which are all closely linked to cognition, spirit, and emotion in brain. Furthermore, the degrees of node in frontal, temporal, and whole brain are increased significantly or extreme significantly with p < 0.05, p < 0.05, and p < 0.01, respectively; clustering coefficient in frontal, temporal, and whole brain are all statistically significant (p < 0.05). The information transmission efficiency of cerebral cortex has been greatly improved. During PC7 stimulation, the topological changes in the activation of cerebral regions and cortical functional networks are consistent with the therapeutic effect, which may provide theoretical support for acupoint stimulation to regulate nerve function.
采用标准低分辨率脑电断层扫描(sLORETA)、锁相值(PLV)和复杂网络3个模块,构建21例健康人经皮穴位电刺激(TEAS)时脑电信号的大脑皮层功能网络。通过比较静息状态和非穴位刺激对PC7刺激触发的脑功能网络的影响。结果表明,PC7刺激主要激活额叶和颞叶,包括前额叶皮质(BA10)、岛叶(BA13)、颞回(BA22)、前扣带皮质(BA32)、颞极(BA38)、背外侧前额叶皮质(BA46)和下额叶皮质(BA47),这些区域与大脑的认知、精神和情感密切相关。此外,随着p p p p的增加,额叶、颞叶和全脑的结度显著或极显著增加
期刊介绍:
Clinical EEG and Neuroscience conveys clinically relevant research and development in electroencephalography and neuroscience. Original articles on any aspect of clinical neurophysiology or related work in allied fields are invited for publication.