Silica Exposure and Cardiovascular, Cerebrovascular, and Respiratory Morbidity in a Cohort of Male Swedish Iron Foundry Workers.

IF 2.3 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Journal of Occupational and Environmental Medicine Pub Date : 2023-09-01 DOI:10.1097/JOM.0000000000002890

Lena Andersson, Alexander Hedbrant, Ing-Liss Bryngelsson, Per Vihlborg, Eva Särndahl, Håkan Westberg

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引用次数: 0

Abstract

Objective: We present quantitative exposure-response data on silica exposure in male Swedish iron foundry workers for cardiovascular, cerebrovascular, and respiratory morbidity.

Methods: This research is a cohort study of 2063 male Swedish iron foundry workers. From the Swedish National Patient Registers, data on morbidity incidence were retrieved. A historical measurement database of 1667 respirable silica exposure measurements from 10 Swedish iron foundries was used to calculate the cumulative exposure dose for each worker.

Results: Increased morbidity risk for the whole group of foundry workers was determined for ischemic heart disease, cerebrovascular disease, chronic obstructive pulmonary disease (COPD), bronchitis, and pneumonia. In addition, an increased risk for COPD at cumulative silica exposures ranging from 0.11 to 0.84 mg/m 3 year is presented.

Conclusions: The study presents a significantly increased COPD risk at cumulative silica exposures below the Swedish occupational exposure limit.

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二氧化硅暴露和心脑血管及呼吸系统疾病在瑞典男性铸铁工人队列中。

目的:我们提供了瑞典男性铁铸造工人的二氧化硅暴露对心血管、脑血管和呼吸系统疾病的定量暴露-反应数据。方法:本研究对2063名瑞典男性铸铁工人进行队列研究。从瑞典国家患者登记册中检索到发病率数据。使用来自10个瑞典铸铁厂的1667次可吸入二氧化硅暴露的历史测量数据库来计算每个工人的累积暴露剂量。结果:铸造工人患缺血性心脏病、脑血管疾病、慢性阻塞性肺疾病(COPD)、支气管炎和肺炎的风险增加。此外，累积二氧化硅暴露在0.11至0.84 mg/m / 3年期间，COPD风险增加。结论:该研究表明，累积二氧化硅暴露低于瑞典职业暴露限值时，COPD风险显著增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Occupational and Environmental Medicine 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

9.40%

发文量

402

审稿时长

3-8 weeks

期刊介绍： Journal of Occupational and Environmental Medicine is an indispensable guide to good health in the workplace for physicians, nurses, and researchers alike. In-depth, clinically oriented research articles and technical reports keep occupational and environmental medicine specialists up-to-date on new medical developments in the prevention, diagnosis, and rehabilitation of environmentally induced conditions and work-related injuries and illnesses.