Trends in Healthcare Resource Use Preceding Diagnosis of Alzheimer's Disease Dementia.

Q1 Neuroscience

International Journal of Alzheimer's Disease Pub Date : 2023-01-01 DOI:10.1155/2023/8154701

Ibrahim M Abbass, Dae Choi, Christopher Wallick, Sheila Seleri Assunção

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引用次数: 2

Abstract

Introduction: An Alzheimer's disease (AD) dementia diagnosis is often preceded by an extended period of cognitive decline. Few studies have examined healthcare resource use (HRU) during an extended period before AD dementia diagnosis.

Methods: In a historical claims-based cohort study, propensity score-matched cohorts of patients with and without AD dementia were observed for a 5-year prediagnosis period and a 1-year postdiagnosis period. Demographics, clinical characteristics, and HRU were compared between groups.

Results: Individuals in the AD dementia group displayed a greater level of medical complexity in the year before diagnosis of AD dementia relative to those in the matched cohort. Both all-cause and AD dementia complication-related HRU increased gradually, with a marked spike at the time of initial AD dementia diagnosis. Discussion. Further research into the natural history of patients with AD dementia is necessary to improve identification of early AD and to better understand its broader impact.

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阿尔茨海默病痴呆诊断前医疗资源使用趋势

简介:阿尔茨海默病(AD)痴呆症的诊断通常是在认知能力下降的延长期之前。很少有研究在AD痴呆诊断前的较长时间内检查医疗资源使用(HRU)。方法:在一项基于历史索赔的队列研究中，在诊断前5年和诊断后1年观察AD痴呆患者和非AD痴呆患者的倾向评分匹配队列。比较两组人口统计学、临床特征和HRU。结果:相对于匹配的队列，AD痴呆组的个体在AD痴呆诊断前一年表现出更高的医疗复杂性。全因和AD痴呆并发症相关HRU均逐渐升高，在AD痴呆初始诊断时出现明显的峰值。讨论。进一步研究阿尔茨海默病痴呆患者的自然史对于提高早期阿尔茨海默病的识别并更好地了解其广泛影响是必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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