Lung Transplantation for COVID-19 Acute Respiratory Distress Syndrome: The British Columbian Experience With New Disease Pathology

IF 2.6 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Seminars in Thoracic and Cardiovascular Surgery Pub Date : 2024-12-01 DOI:10.1053/j.semtcvs.2022.12.004

Roy Avraham Hilzenrat MD, MHSc , John C. English MD , Anna McGuire MD, MSc , Gordon Finlayson MD , James Choi MD, MPH , John Yee MD

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引用次数: 0

Abstract

Lung transplantation is a life-saving treatment for patients with end-stage lung disease. COVID-19 has been associated with a severe and rapid decline in pulmonary function, in which case lung transplantation has been described to be effective. We herein describe 9 patients who underwent lung transplantation for COVID-19 acute respiratory distress syndrome, of whom 6 were bridged with extracorporeal membrane oxygenation (ECMO). The median time of pre-operative observation periods was 54 days to ensure no lung function recovery and the time to wean off extracorporeal membrane oxygenation was 3 days. Patients had comparable short-term survival outcomes to non-COVID-19 lung transplant recipients at our institution during the same time period. Lung transplantation for COVID-19-associated lung disease is feasible with comparable short-term outcomes and may liberate patients from extracorporeal supports.

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肺移植治疗 COVID-19 急性呼吸窘迫综合征：不列颠哥伦比亚省的新病理经验。

肺移植是挽救终末期肺病患者生命的一种治疗方法。COVID-19 与肺功能严重急剧下降有关，在这种情况下，肺移植被认为是有效的。我们在本文中描述了 9 名因 COVID-19 急性呼吸窘迫综合征而接受肺移植的患者，其中 6 人接受了体外膜肺氧合（ECMO）。为确保肺功能不恢复，术前观察期的中位时间为 54 天，脱离体外膜氧合的时间为 3 天。在同一时期，患者的短期生存结果与本院非 COVID-19 肺移植受者相当。COVID-19相关肺病的肺移植手术是可行的，短期疗效相当，而且可以让患者摆脱体外支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in Thoracic and Cardiovascular Surgery Medicine-Pulmonary and Respiratory Medicine

CiteScore

5.80

自引率

0.00%

发文量

324

审稿时长

12 days

期刊介绍： Seminars in Thoracic and Cardiovascular Surgery is devoted to providing a forum for cardiothoracic surgeons to disseminate and discuss important new information and to gain insight into unresolved areas of question in the specialty. Each issue presents readers with a selection of original peer-reviewed articles accompanied by editorial commentary from specialists in the field. In addition, readers are offered valuable invited articles: State of Views editorials and Current Readings highlighting the latest contributions on central or controversial issues. Another prized feature is expert roundtable discussions in which experts debate critical questions for cardiothoracic treatment and care. Seminars is an invitation-only publication that receives original submissions transferred ONLY from its sister publication, The Journal of Thoracic and Cardiovascular Surgery. As we continue to expand the reach of the Journal, we will explore the possibility of accepting unsolicited manuscripts in the future.