Bacterial Metabolism-Initiated Nanocatalytic Tumor Immunotherapy

IF 31.6 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nano-Micro Letters Pub Date : 2022-11-11 DOI:10.1007/s40820-022-00951-0

Wencheng Wu, Yinying Pu, Shuang Gao, Yucui Shen, Min Zhou, Heliang Yao, Jianlin Shi

引用次数: 0

Abstract

Highlights

Novel-designed microbiotic nanomedicine capable of targeting hypoxic tumor sites.
First paradigm of bacterial metabolism-initiated and photothermal therapy-enhanced nanocatalytic therapy for ablating tumors and inducing immunogenic cell death.
Strong antitumor immunity activation for abscopal tumors therapy.

Abstract Image

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细菌代谢引发的纳米催化肿瘤免疫疗法

亮点新型设计的微生物纳米药物能够靶向缺氧肿瘤部位。首个由细菌代谢引发、光热疗法增强的纳米催化疗法范例，用于消融肿瘤和诱导免疫性细胞死亡。激活强大的抗肿瘤免疫力，用于腹腔肿瘤治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

42.40

自引率

4.90%

发文量

715

审稿时长

13 weeks

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary and open-access journal that focus on science, experiments, engineering, technologies and applications of nano- or microscale structure and system in physics, chemistry, biology, material science, pharmacy and their expanding interfaces with at least one dimension ranging from a few sub-nanometers to a few hundreds of micrometers. Especially, emphasize the bottom-up approach in the length scale from nano to micro since the key for nanotechnology to reach industrial applications is to assemble, to modify, and to control nanostructure in micro scale. The aim is to provide a publishing platform crossing the boundaries, from nano to micro, and from science to technologies.