The analysis of multiple outcomes, multiple variables and variables selection in hematopoietic cell transplantation studies

IF 2.2 4区医学 Q3 HEMATOLOGY

Best Practice & Research Clinical Haematology Pub Date : 2023-09-01 DOI:10.1016/j.beha.2023.101478

Soyoung Kim , Xi Fang , Kwang Woo Ahn

引用次数: 0

Abstract

It is common to study time-to-event data in cancer research such as hematopoietic cell transplantation (HCT) for leukemia. The extensive work has been done for the univariate survival outcome, that is, one event type. However, in practice a subject is often exposed to multiple types of outcomes. In this article, we review various types of right-censored data with multiple outcome types including competing risks data, recurrent event data, and composite endpoints. We also provide hematopoietic cell transplantation data examples.

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造血细胞移植研究的多结局、多变量及变量选择分析

在癌症研究中，研究时间-事件数据是很常见的，如白血病的造血细胞移植（HCT）。对于单变量生存结果，即一种事件类型，已经做了大量的工作。然而，在实践中，受试者往往会接触到多种类型的结果。在这篇文章中，我们回顾了各种类型的具有多种结果类型的权利审查数据，包括竞争风险数据、复发事件数据和复合终点。我们还提供了造血细胞移植的数据实例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best Practice & Research Clinical Haematology 医学-血液学

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

35 days

期刊介绍： Best Practice & Research Clinical Haematology publishes review articles integrating the results from the latest original research articles into practical, evidence-based review articles. These articles seek to address the key clinical issues of diagnosis, treatment and patient management. Each issue follows a problem-orientated approach which focuses on the key questions to be addressed, clearly defining what is known and not known, covering the spectrum of clinical and laboratory haematological practice and research. Although most reviews are invited, the Editor welcomes suggestions from potential authors.