Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial.

IF 2.1 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Psychosomatic Obstetrics & Gynecology Pub Date : 2022-12-01 DOI:10.1080/0167482X.2021.1985452

Maryam Shirzadi, Negin Farshchian, Arash Nazarpour, Soudabeh Eskandari, Fahimeh Kahrari, Hamed Abdollahpour Ranjbar, Somayeh Nazari, Issa Hekmati, Sara Farhang

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引用次数: 0

Abstract

Introduction: Available treatments for hot flashes in patients with breast cancer are not always tolerable or effective for all patients.

Methods: Patients diagnosed to have primary breast cancer were randomly allocated to receive 10 mg of escitalopram, placebo, or progressive muscle relaxation therapy. Patients were asked to report the frequency and duration of hot flashes during day and night, at baseline and after ten weeks of treatment, and completed the menopause rating scale.

Results: Eighty-two patients were randomly assigned to receive escitalopram (n = 26), PMRT (n = 28), and placebo (n = 28). PMRT and escitalopram could effectively decrease number and duration of diurnal and nocturnal HFs in patients with breast cancer, with a better effect observed from escitalopram. They could both decrease the total score of MRS.

Conclusion: Both escitalopram ad PMRT can reveal nocturnal and diurnal HFs in terms of frequency and duration in patients with breast cancer.

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艾司西酞普兰和渐进式肌肉放松训练对治疗乳腺癌患者潮热都有效:一项随机对照试验。

导读:现有的治疗方法对乳腺癌患者潮热并不总是耐受或有效的所有患者。方法:诊断为原发性乳腺癌的患者被随机分配接受10mg艾司西酞普兰、安慰剂或渐进式肌肉放松疗法。患者被要求报告白天和晚上潮热的频率和持续时间，在基线和治疗10周后，并完成更年期评分量表。结果:82例患者被随机分配到艾司西酞普兰(n = 26)、PMRT (n = 28)和安慰剂(n = 28)组。PMRT和艾司西酞普兰能有效减少乳腺癌患者夜间和夜间hf的次数和持续时间，艾司西酞普兰效果更好。结论:艾司西酞普兰和PMRT均能揭示乳腺癌患者夜间和日间HFs发生的频率和持续时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Psychosomatic Obstetrics & Gynecology 医学-妇产科学

CiteScore

6.10

自引率

3.20%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Psychosomatic Obstetrics and Gynecology was founded in 1982 in order to provide a scientific forum for obstetricians, gynecologists, psychiatrists and psychologists, academic health professionals as well as for all those who are interested in the psychosocial and psychosomatic aspects of women’s health. Another of its aims is to stimulate obstetricians and gynecologists to pay more attention to this very important facet of their profession.