The Sonographic Features of Malformation in Fetal Echogenic Bowel and Its Relationship With Chromosome Abnormalities.

IF 0.7 4区 医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Lin Yang, Huie Chen, Feifei Li, Jianmei Liao, Xiangbo Lin
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引用次数: 2

Abstract

Abstract: The aims of this study were to analyze the sonographic features and clinical prognosis of fetal echogenic bowel (FEB) and to evaluate the value of FEB in the prediction of fetal chromosomal abnormalities. Eight hundred eighty-two fetuses with FEB were selected. The ultrasonographic features and the chromosomal examination were retrospectively analyzed. Among the 882 FEB, 272 (30.8%) cases had malformation. The most common malformation was cardiovascular malformation (21.6%), followed by urinary malformation (9.0%), craniocerebral malformation (6.8%), and gastrointestinal malformations (5.6%). According to other combined ultrasound abnormalities, the FEBs were divided into 4 groups: isolated FEB group (490 cases), ultrasound soft indicators group (130 cases), single malformation group (117 cases), and multiple malformation group (145 cases). A total of 45 cases (5.1%) were detected with chromosomal abnormalities. Compared with isolated FEB group, the rate of chromosomal abnormality in other 3 groups was significantly higher. Among 490 cases of isolated FEB, 114 cases of isolated FEB group with adverse pregnancy outcomes were selected as the experimental group, and 376 cases of FEB group with good prognosis were selected as the control group. There were significant differences of the location, shape, intensity, and progression between the 2 groups. Multivariate logistic regression analysis showed that central location and progression of FEB were independent risk predictors of poor prognosis. The combined malformation rate is high for FEB fetuses. The fetal systems should be carefully examined when FEB is found in prenatal ultrasound.

胎儿回声肠畸形的超声特征及其与染色体异常的关系。
摘要:本研究旨在分析胎儿回声肠(FEB)的声像图特征及临床预后,探讨FEB在胎儿染色体异常预测中的价值。选择882例FEB胎儿。回顾性分析其超声表现及染色体检查。882例FEB中畸形272例(30.8%)。最常见的畸形是心血管畸形(21.6%),其次是泌尿畸形(9.0%)、颅脑畸形(6.8%)和胃肠道畸形(5.6%)。根据其他超声联合异常情况将FEB分为4组:孤立FEB组(490例)、超声软指标组(130例)、单一畸形组(117例)、多发性畸形组(145例)。检出染色体异常45例(5.1%)。与孤立FEB组比较,其余3组染色体异常率均显著升高。490例孤立性FEB患者中,选取妊娠结局不良的孤立性FEB组114例作为实验组,选取预后良好的孤立性FEB组376例作为对照组。两组间在位置、形态、强度、进展等方面均有显著差异。多因素logistic回归分析显示,中心位置和进展是预后不良的独立危险预测因素。FEB胎儿的综合畸形率很高。当产前超声检查发现FEB时,应仔细检查胎儿系统。
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来源期刊
Ultrasound Quarterly
Ultrasound Quarterly RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.50
自引率
7.70%
发文量
105
审稿时长
>12 weeks
期刊介绍: Ultrasound Quarterly provides coverage of the newest, most sophisticated ultrasound techniques as well as in-depth analysis of important developments in this dynamic field. The journal publishes reviews of a wide variety of topics including trans-vaginal ultrasonography, detection of fetal anomalies, color Doppler flow imaging, pediatric ultrasonography, and breast sonography. Official Journal of the Society of Radiologists in Ultrasound
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