Sublingual microcirculation in healthy pediatric population using the sidestream dark-field imaging method.

IF 2.1 4区 医学 Q3 HEMATOLOGY
Vlasta Krausova, David Neumann, Jaroslav Kraus, Vlasta Dostalova, Pavel Dostal
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引用次数: 0

Abstract

Background: The sidestream dark-field imaging method is used to study microcirculation. Normal values of sublingual microcirculation parameters in healthy children of different age and gender categories are unknown.

Objective: The study's main goal was to determine normal values of selected parameters of sublingual microcirculation in healthy children of different age and gender categories.

Methods: 40 healthy children were measured, ten aged 3-5.9 years, ten aged 6-10.9 years, ten aged 11-14.9 years, and ten aged 15-18.9 years. After recording the basic anthropometric parameters and vital functions, each volunteer had their microcirculation measured using an SDF probe placed sublingually. Three video clips were recorded and processed offline, and the three best and most stable parts of each were analyzed.

Results: Total vascular density, small vessel density, proportion of perfused small vessels, perfused vessel density, perfused small vessel density, and DeBacker's score were significantly higher in females than in males. There were no differences between age groups in microcirculation parameters except MFI.

Conclusions: Age does not influence normal values of microcirculatory parameters. Female gender was associated with higher vessel density, perfused vessel density, and DeBacker's score. A suggestion of the normal range of microcirculatory parameters in healthy children is provided.

用侧流暗场显像法观察健康儿童的舌下微循环。
背景:采用侧流暗场成像方法研究微循环。不同年龄和性别类别的健康儿童舌下微循环参数的正常值尚不清楚。目的:本研究的主要目的是确定不同年龄和性别类别的健康儿童舌下微循环选定参数的正常值。方法:对40名健康儿童进行测量,年龄分别为3-5.9岁、6-10.9岁、11-14.9岁和15-18.9岁各10名。在记录了基本的人体测量参数和生命功能后,每个志愿者都使用放置在舌下的SDF探针测量微循环。三个视频剪辑被离线录制和处理,并分析了每个视频剪辑中最好和最稳定的三个部分。结果:女性的总血管密度、小血管密度、灌注小血管比例、灌注血管密度、灌流小血管密度和DeBacker评分显著高于男性。除MFI外,各年龄组微循环参数无差异。结论:年龄不影响微循环参数的正常值。女性与较高的血管密度、灌注血管密度和DeBacker评分相关。提出了健康儿童微循环参数正常范围的建议。
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来源期刊
CiteScore
4.30
自引率
33.30%
发文量
170
期刊介绍: Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
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