Cost-utility study of home-based cryotherapy device for wart treatment: a randomized, controlled, and investigator-blinded trial.

IF 2.9 4区医学 Q2 DERMATOLOGY

Journal of Dermatological Treatment Pub Date : 2022-12-01 DOI:10.1080/09546634.2022.2114782

Nattanichcha Kulthanachairojana, Suthira Taychakhoonavudh, Kanokvalai Kulthanan, Sumanas Bunyaratavej, Sasima Eimpunth, Bawonpak Pongkittilar, Suthasanee Prasertsook, Supisara Wongdama, Charussri Leeyaphan

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引用次数: 0

Abstract

Background: Cryotherapy is typically performed by physicians. No cost-utility studies of home-based cryotherapy have been reported.

Objectives: To study the cost utility of home-based cryotherapy devices and in-hospital liquid nitrogen therapy for cutaneous warts.

Materials and methods: This randomized, controlled, investigator-blinded trial was carried out on patients with cutaneous warts. Participants were randomly assigned to two groups: home-based cryotherapy and in-hospital liquid nitrogen therapy. Clinical examinations were conducted at baseline and monthly until cure, and outcomes (cure rate, side effects, total costs, and quality of life) were compared. A cost-utility analysis was performed.

Results: Nineteen of 22 patients completed the treatment and were analyzed. The efficacy of home-based cryotherapy and in-hospital therapy was 72.8% and 64.3%, respectively. Side effects (pain, redness, and burning) were observed. The mean numbers of medical visits were 2.83 for home-based therapy and 3.30 for in-hospital therapy. The total costs for home-based therapy and the in-hospital therapy were US $76.03 and $100.45, respectively. The home-based therapy had 0.2297 quality-adjusted life years, slightly higher than the corresponding value of 0.2254 for in-hospital therapy.

Conclusions: Home-based cryotherapy devices are a cost-saving strategy with similar efficacy to in-hospital liquid nitrogen therapy.

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家庭冷冻治疗装置治疗疣的成本-效用研究:一项随机、对照、研究者盲法试验。

背景:冷冻治疗通常由医生进行。没有关于家庭冷冻疗法的成本效用研究的报道。目的:探讨家用冷冻治疗装置和住院液氮治疗皮肤疣的成本效益。材料和方法:这项随机、对照、研究者盲法试验在皮肤疣患者中进行。参与者被随机分为两组:家庭冷冻疗法和医院液氮疗法。在基线和每月进行临床检查，直到治愈，并比较结果(治愈率，副作用，总成本和生活质量)。进行了成本效用分析。结果:22例患者中有19例完成治疗并进行分析。家庭冷冻治疗和住院冷冻治疗的有效率分别为72.8%和64.3%。观察了副作用(疼痛、发红、灼烧)。家庭治疗的平均诊疗次数为2.83次，住院治疗的平均诊疗次数为3.30次。家庭治疗和住院治疗的总费用分别为76.03美元和100.45美元。家庭治疗的质量调整生命年为0.2297，略高于住院治疗的相应值0.2254。结论:家庭冷冻装置是一种节省成本的策略，其效果与医院液氮治疗相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Dermatological Treatment 医学-皮肤病学

CiteScore

6.50

自引率

0.00%

发文量

145

审稿时长

6-12 weeks

期刊介绍： The Journal of Dermatological Treatment covers all aspects of the treatment of skin disease, including the use of topical and systematically administered drugs and other forms of therapy. The Journal of Dermatological Treatment is positioned to give dermatologists cutting edge information on new treatments in all areas of dermatology. It also publishes valuable clinical reviews and theoretical papers on dermatological treatments.