The Genomics Organization for Academic Laboratories (GOAL): A vision for a genomics future for academic pathology

IF 1.2 Q3 PATHOLOGY

Academic Pathology Pub Date : 2023-07-01 DOI:10.1016/j.acpath.2023.100090

Dara L. Aisner MD, PhD , Christopher D. Gocke MD , Daniel Jones MD, PhD , Melvin Limson PhD , Jennifer Morrissette MD , Jeremy P. Segal MD, PhD

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引用次数: 1

Abstract

Innovative and self-sustaining clinical genomics laboratories specializing in cutting-edge oncology testing are critical to the success of academic pathology departments and resident and fellow education in molecular pathology. However, the pressures and challenges facing these laboratories are numerous, including the complexities of validating comprehensive cancer next-generation sequencing (NGS) panels, competition from commercial laboratories, and the reimbursement and regulatory hurdles inherent in high-complexity testing. Cross-institutional collaborations, including shared assay content and interpretative frameworks, are a valuable element to academic laboratory success. To address these and other needs, the Genomics Organization for Academic Laboratories (GOAL) was conceived in 2018, incorporated in 2020 and has grown to include 29 participating institutions in 2022. Here, we describe the mission of GOAL, its structure, and the outcomes and projects undertaken in its first years.

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学术实验室基因组学组织(GOAL):对学术病理学基因组学未来的展望

专门从事尖端肿瘤学测试的创新和自我维持的临床基因组学实验室对病理学学术部门以及分子病理学住院医师和研究员教育的成功至关重要。然而，这些实验室面临的压力和挑战是巨大的，包括验证全面的癌症下一代测序（NGS）面板的复杂性、来自商业实验室的竞争，以及高复杂度测试固有的报销和监管障碍。跨机构合作，包括共享分析内容和解释框架，是学术实验室成功的宝贵因素。为了满足这些和其他需求，学术实验室基因组学组织（GOAL）于2018年成立，并于2020年成立，到2022年已发展到包括29个参与机构。在这里，我们描述了GOAL的使命、结构以及最初几年的成果和项目。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Academic Pathology PATHOLOGY-

CiteScore

2.20

自引率

20.00%

发文量

审稿时长

15 weeks

期刊介绍： Academic Pathology is an open access journal sponsored by the Association of Pathology Chairs, established to give voice to the innovations in leadership and management of academic departments of Pathology. These innovations may have impact across the breadth of pathology and laboratory medicine practice. Academic Pathology addresses methods for improving patient care (clinical informatics, genomic testing and data management, lab automation, electronic health record integration, and annotate biorepositories); best practices in inter-professional clinical partnerships; innovative pedagogical approaches to medical education and educational program evaluation in pathology; models for training academic pathologists and advancing academic career development; administrative and organizational models supporting the discipline; and leadership development in academic medical centers, health systems, and other relevant venues. Intended authorship and audiences for Academic Pathology are international and reach beyond academic pathology itself, including but not limited to healthcare providers, educators, researchers, and policy-makers.