Associations between Physical Exercise, Quality of Life, Psychological Symptoms and Treatment Side Effects in Early Breast Cancer.

IF 1.9 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Breast Journal Pub Date : 2022-01-01 DOI:10.1155/2022/9921575

Leena Vehmanen, Johanna Mattson, Evangelos Karademas, Albino J Oliveira-Maia, Berta Sousa, Ruth Pat-Horenczyk, Ketti Mazzocco, Panagiotis Simos, Fátima Cardoso, Greta Pettini, Chiara Marzorati, Eleni Kolokotroni, Georgios Stamatakos, Diana Frasquilho, Paula Poikonen-Saksela

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引用次数: 1

Abstract

Background: Identifying and understanding modifiable factors for the well-being of cancer patients is critical in survivorship research. We studied variables associated with the exercise habits of breast cancer patients and investigated if the achievement of exercise recommendations was associated with enhanced quality of life and/or psychological well-being. Material and Methods. 311 women from Finland, Portugal, Israel, and Italy receiving adjuvant therapy for stage I-III breast cancer answered questions about sociodemographic factors and physical exercise. Quality of life was assessed by the EORTC C30 and BR23 questionnaires. Anxiety and depression were evaluated using the HADS scale.

Results: At the beginning of adjuvant therapy and after twelve months, 32% and 26% of participants were physically inactive, 27% and 30% exercised between 30 and 150 minutes per week, while 41% and 45% exercised the recommended 150 minutes or more per week. Relative to other countries, Finnish participants were more likely to be active at baseline and at twelve months (89% vs. 50%, p < 0.001 and 87% vs. 64%, p < 0.001). Participants with stage I cancer were more likely to be active at twelve months than those with a higher stage (80% vs. 70%,p < 0.05). The inactive participants reported more anxiety (p < 0.05) and depression (p < 0.001), lower global quality of life (p < 0.001), and more side effects (p < 0.05) than the others at twelve months. Accordingly, those who remained inactive or decreased their level of exercise from baseline to twelve months reported more anxiety (p < 0.01) and depression (p < 0.001), lower global quality of life (p < 0.001), and more side effects (p < 0.05) than those with the same or increased level of exercise.

Conclusion: For women with early breast cancer, exercise was associated with a better quality of life, less depression and anxiety, and fewer adverse events of adjuvant therapy. Trial registration number: NCT05095675. Paula Poikonen-Saksela on behalf of Bounce consortium (https://www.bounce-project.eu/).

查看原文本刊更多论文

早期乳腺癌的体育锻炼、生活质量、心理症状和治疗副作用之间的关系

背景:识别和理解癌症患者健康状况的可改变因素在生存研究中至关重要。我们研究了与乳腺癌患者运动习惯相关的变量，并调查了运动建议的实现是否与提高生活质量和/或心理健康有关。材料和方法:来自芬兰、葡萄牙、以色列和意大利的311名接受I-III期乳腺癌辅助治疗的妇女回答了有关社会人口因素和体育锻炼的问题。生活质量通过EORTC C30和BR23问卷进行评估。焦虑和抑郁采用HADS量表进行评估。结果:在辅助治疗开始和12个月后，32%和26%的参与者不运动，27%和30%的参与者每周运动30到150分钟，而41%和45%的参与者每周运动150分钟或更长时间。相对于其他国家，芬兰参与者在基线和12个月时更有可能保持活跃(89%对50%，p < 0.001, 87%对64%，p < 0.001)。I期癌症患者在12个月时的活动量比分期更高的患者高(80%比70%，p < 0.05)。在12个月时，不运动的参与者比其他人报告了更多的焦虑(p < 0.05)和抑郁(p < 0.001)，更低的整体生活质量(p < 0.001)和更多的副作用(p < 0.05)。因此，那些从基线到12个月保持不运动或减少运动水平的人报告的焦虑(p < 0.01)和抑郁(p < 0.001)，整体生活质量(p < 0.001)较低，副作用(p < 0.05)多于运动水平相同或增加的人。结论:对于早期乳腺癌女性，运动与更好的生活质量、更少的抑郁和焦虑以及更少的辅助治疗不良事件有关。试验注册号:NCT05095675。Paula Poikonen-Saksela代表Bounce财团(https://www.bounce-project.eu/)。

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来源期刊

Breast Journal 医学-妇产科学

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： The Breast Journal is the first comprehensive, multidisciplinary source devoted exclusively to all facets of research, diagnosis, and treatment of breast disease. The Breast Journal encompasses the latest news and technologies from the many medical specialties concerned with breast disease care in order to address the disease within the context of an integrated breast health care. This editorial philosophy recognizes the special social, sexual, and psychological considerations that distinguish cancer, and breast cancer in particular, from other serious diseases. Topics specifically within the scope of The Breast Journal include: Risk Factors Prevention Early Detection Diagnosis and Therapy Psychological Issues Quality of Life Biology of Breast Cancer.