MEASURING PERFORMANCE FOR END-OF-LIFE CARE.

IF 1.3 4区 数学 Q2 STATISTICS & PROBABILITY
Sebastien Haneuse, Deborah Schrag, Francesca Dominici, Sharon-Lise Normand, Kyu Ha Lee
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引用次数: 1

Abstract

Although not without controversy, readmission is entrenched as a hospital quality metric with statistical analyses generally based on fitting a logistic-Normal generalized linear mixed model. Such analyses, however, ignore death as a competing risk, although doing so for clinical conditions with high mortality can have profound effects; a hospital's seemingly good performance for readmission may be an artifact of it having poor performance for mortality. in this paper we propose novel multivariate hospital-level performance measures for readmission and mortality that derive from framing the analysis as one of cluster-correlated semi-competing risks data. We also consider a number of profiling-related goals, including the identification of extreme performers and a bivariate classification of whether the hospital has higher-/lower-than-expected readmission and mortality rates via a Bayesian decision-theoretic approach that characterizes hospitals on the basis of minimizing the posterior expected loss for an appropriate loss function. in some settings, particularly if the number of hospitals is large, the computational burden may be prohibitive. To resolve this, we propose a series of analysis strategies that will be useful in practice. Throughout, the methods are illustrated with data from CMS on N = 17,685 patients diagnosed with pancreatic cancer between 2000-2012 at one of J = 264 hospitals in California.

衡量临终关怀的表现。
虽然并非没有争议,但再入院率被确立为医院质量指标,其统计分析通常基于拟合logistic-Normal广义线性混合模型。然而,这种分析忽略了死亡作为一种竞争风险,尽管对高死亡率的临床条件这样做可能会产生深远的影响;一家医院在再入院率方面表现良好,可能是它在死亡率方面表现不佳的假象。在本文中,我们提出了新的多变量医院水平的再入院和死亡率的绩效指标,这些指标来源于将分析框架作为集群相关的半竞争风险数据之一。我们还考虑了一些与分析相关的目标,包括识别极端表现者,以及通过贝叶斯决策理论方法对医院是否有高于/低于预期的再入院率和死亡率进行双变量分类,该方法以最小化适当损失函数的后验预期损失为基础来表征医院。在某些情况下,特别是在医院数量众多的情况下,计算负担可能令人望而却步。为了解决这个问题,我们提出了一系列在实践中有用的分析策略。在整个过程中,这些方法用CMS对2000年至2012年间在加利福尼亚州J = 264家医院中的一家诊断为胰腺癌的N = 17,685例患者的数据进行了说明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Annals of Applied Statistics
Annals of Applied Statistics 社会科学-统计学与概率论
CiteScore
3.10
自引率
5.60%
发文量
131
审稿时长
6-12 weeks
期刊介绍: Statistical research spans an enormous range from direct subject-matter collaborations to pure mathematical theory. The Annals of Applied Statistics, the newest journal from the IMS, is aimed at papers in the applied half of this range. Published quarterly in both print and electronic form, our goal is to provide a timely and unified forum for all areas of applied statistics.
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