{"title":"Deep-Data-Driven Neural Networks for COVID-19 Vaccine Efficacy.","authors":"Thomas K Torku, Abdul Q M Khaliq, Khaled M Furati","doi":"10.3390/epidemiologia2040039","DOIUrl":null,"url":null,"abstract":"<p><p>Vaccination strategies to lessen the impact of the spread of a disease are fundamental to public health authorities and policy makers. The socio-economic benefit of full return to normalcy is the core of such strategies. In this paper, a COVID-19 vaccination model with efficacy rate is developed and analyzed. The epidemiological parameters of the model are learned via a feed-forward neural network. A hybrid approach that combines residual neural network with variants of recurrent neural network is implemented and analyzed for reliable and accurate prediction of daily cases. The error metrics and a k-fold cross validation with random splitting reveal that a particular type of hybrid approach called residual neural network with gated recurrent unit is the best hybrid neural network architecture. The data-driven simulations confirm the fact that the vaccination rate with higher efficacy lowers the infectiousness and basic reproduction number. As a study case, COVID-19 data for the state of Tennessee in USA is used.</p>","PeriodicalId":72944,"journal":{"name":"Epidemiolgia (Basel, Switzerland)","volume":"2 4","pages":"564-586"},"PeriodicalIF":0.0000,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9620931/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Epidemiolgia (Basel, Switzerland)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/epidemiologia2040039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Vaccination strategies to lessen the impact of the spread of a disease are fundamental to public health authorities and policy makers. The socio-economic benefit of full return to normalcy is the core of such strategies. In this paper, a COVID-19 vaccination model with efficacy rate is developed and analyzed. The epidemiological parameters of the model are learned via a feed-forward neural network. A hybrid approach that combines residual neural network with variants of recurrent neural network is implemented and analyzed for reliable and accurate prediction of daily cases. The error metrics and a k-fold cross validation with random splitting reveal that a particular type of hybrid approach called residual neural network with gated recurrent unit is the best hybrid neural network architecture. The data-driven simulations confirm the fact that the vaccination rate with higher efficacy lowers the infectiousness and basic reproduction number. As a study case, COVID-19 data for the state of Tennessee in USA is used.