Potency and safety analysis of hemp delta-9 products: the hemp vs. cannabis demarcation problem.

Lee Johnson, Marc Malone, Erik Paulson, Josh Swider, David Marelius, Susan Andersen, Dominic Black
{"title":"Potency and safety analysis of hemp delta-9 products: the hemp vs. cannabis demarcation problem.","authors":"Lee Johnson, Marc Malone, Erik Paulson, Josh Swider, David Marelius, Susan Andersen, Dominic Black","doi":"10.1186/s42238-023-00197-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hemp-derived delta-9 tetrahydrocannabinol (∆<sup>9</sup> THC) products are freely available for sale across much of the USA, but the federal legislation allowing their sale places only minimal requirements on companies. Products must contain no more than 0.3% ∆<sup>9</sup> THC by dry weight, but no limit is placed on overall dosage and there is no requirement that products are tested. However, some states-such as Colorado-specifically prohibit products created by \"chemically modifying\" a natural hemp component.</p><p><strong>Methods: </strong>Fifty-three ∆<sup>9</sup> THC products were ordered and submitted to InfiniteCAL laboratory for analysis. The lab analysis considered potency, the presence of impurities, and whether the ∆<sup>9</sup> THC present was natural or converted from CBD. The presence of age verification, company-conducted testing, and warning labels was also considered.</p><p><strong>Results: </strong>While 96.2% of products were under the legal ∆9 THC limit, 66.0% differed from their stated dosage by more than 10%, and although 84.9% provided a lab report to customers, 71.1% of these did not check for impurities. Additionally, 49% of products converted CBD to THC to achieve their levels, and only 15.1% performed age verification at checkout.</p><p><strong>Conclusions: </strong>Despite some positive findings, the results show that hemp ∆<sup>9</sup> THC companies offer inaccurately labeled products that contain more THC than would be allowed in adult-use states. This raises serious issues around consumer safety, and consent when consuming intoxicating products. Steps to boost accountability for companies must be considered by either the industry or lawmakers if intoxicating hemp products are to remain on the market safely.</p>","PeriodicalId":15172,"journal":{"name":"Journal of Cannabis Research","volume":"5 1","pages":"29"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369762/pdf/","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cannabis Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s42238-023-00197-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

Background: Hemp-derived delta-9 tetrahydrocannabinol (∆9 THC) products are freely available for sale across much of the USA, but the federal legislation allowing their sale places only minimal requirements on companies. Products must contain no more than 0.3% ∆9 THC by dry weight, but no limit is placed on overall dosage and there is no requirement that products are tested. However, some states-such as Colorado-specifically prohibit products created by "chemically modifying" a natural hemp component.

Methods: Fifty-three ∆9 THC products were ordered and submitted to InfiniteCAL laboratory for analysis. The lab analysis considered potency, the presence of impurities, and whether the ∆9 THC present was natural or converted from CBD. The presence of age verification, company-conducted testing, and warning labels was also considered.

Results: While 96.2% of products were under the legal ∆9 THC limit, 66.0% differed from their stated dosage by more than 10%, and although 84.9% provided a lab report to customers, 71.1% of these did not check for impurities. Additionally, 49% of products converted CBD to THC to achieve their levels, and only 15.1% performed age verification at checkout.

Conclusions: Despite some positive findings, the results show that hemp ∆9 THC companies offer inaccurately labeled products that contain more THC than would be allowed in adult-use states. This raises serious issues around consumer safety, and consent when consuming intoxicating products. Steps to boost accountability for companies must be considered by either the industry or lawmakers if intoxicating hemp products are to remain on the market safely.

Abstract Image

Abstract Image

Abstract Image

大麻delta-9产品的效价和安全性分析:大麻与大麻的界限问题。
背景:大麻衍生的δ -9四氢大麻酚(∆9 THC)产品在美国大部分地区都可以免费销售,但允许其销售的联邦立法对公司的要求很低。产品的THC含量不得超过0.3%(9)(干重),但对总剂量没有限制,也没有要求对产品进行测试。然而,一些州,如科罗拉多州,明确禁止通过“化学修饰”天然大麻成分制造的产品。方法:订购53个∆9 THC产品,提交InfiniteCAL实验室进行分析。实验室分析考虑了效力、杂质的存在,以及存在的∆9 THC是天然的还是从CBD转化而来的。还考虑了年龄验证、公司进行的测试和警告标签的存在。结果:96.2%的产品在规定的(9)THC限量以内,66.0%的产品与规定的剂量相差10%以上,84.9%的产品向客户提供了实验室报告,但其中71.1%没有检查杂质。此外,49%的产品将CBD转化为THC以达到其水平,只有15.1%的产品在结账时进行了年龄验证。结论:尽管有一些积极的发现,但结果表明,大麻∆9 THC公司提供的产品标签不准确,其THC含量超过了成人使用州的允许含量。这引发了关于消费者安全的严重问题,以及在消费令人陶醉的产品时是否同意。如果要让令人陶醉的大麻产品安全地留在市场上,行业或立法者必须考虑加强公司问责制的步骤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信