Patient characteristics may affect the lymphatic staining ability of Indocyanine green and Patent blue during lymphaticovenous anastomosis.

IF 2.1 4区 医学 Q3 HEMATOLOGY
Niklas Biermann, Elisabeth Eschenbacher, Vanessa Brébant, Norbert Heine, Eva Brix, Lukas Prantl, Alexandra M Anker
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引用次数: 0

Abstract

Background: The use of dyes like Indocyanine green (ICG) and Patent blue facilitates the identification of lymphatic vessels during lymphaticovenous anastomosis (LVA) surgery. However, some patients experience "staining failure". In these cases, no stained lymphatic vessels can be detected, making supermicrosurgical LVA even more complex.

Objective: This study aims to investigate patient-related factors that may interfere with lymphatic vessel staining during LVA.

Methods: A retrospective study was conducted on 30 patient charts, focusing on patient characteristics and the staining quality of ICG and Patent blue dye. Statistical analyses were performed to identify correlations between variables.

Results: Significant correlations were found between higher age and secondary lymphedema, longer duration of lymphedema in male patients until surgery and reoccurring cellulitis and Patent blue staining. Notably, recurrent infections to the lymphatic system resulted in inferior staining ability during LVA surgery.

Conclusions: Due to staining failure the detection of functional lymphatic vessels remains challenging in LVA surgery. A more extensive preoperative workup is recommended for patients with recurrent cellulitis to optimize surgical feasibility and procedure quality in LVA treatment for lymphedema.

在淋巴-静脉吻合术中,患者的特征可能会影响吲哚菁绿和专利蓝的淋巴染色能力。
背景:使用靛氰绿(ICG)和专利蓝等染料有助于在淋巴-静脉吻合术(LVA)中识别淋巴管。然而,有些患者会出现 "染色失败"。在这种情况下,无法检测到染色淋巴管,从而使超显微外科淋巴管吻合术变得更加复杂:本研究旨在调查可能干扰 LVA 淋巴管染色的患者相关因素:方法:对 30 份患者病历进行回顾性研究,重点关注患者特征以及 ICG 和专利蓝染料的染色质量。对变量之间的相关性进行了统计分析:结果:研究发现,年龄越大,继发性淋巴水肿越严重;男性患者淋巴水肿持续时间越长,直至手术;再次发生蜂窝织炎和巴特蓝染色之间存在显著相关性。值得注意的是,淋巴系统的反复感染导致 LVA 手术的染色能力下降:结论:由于染色失败,在 LVA 手术中检测功能性淋巴管仍然具有挑战性。建议对复发性蜂窝组织炎患者进行更广泛的术前检查,以优化淋巴水肿 LVA 治疗的手术可行性和手术质量。
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来源期刊
CiteScore
4.30
自引率
33.30%
发文量
170
期刊介绍: Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
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