Antiemetics and Apfel Scores in Orthopedic Surgery.

IF 0.8 Q4 PHARMACOLOGY & PHARMACY
Hospital Pharmacy Pub Date : 2023-10-01 Epub Date: 2023-05-03 DOI:10.1177/00185787231169458
Van N Tran, Brennan J Fitzpatrick, Sourav Das
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引用次数: 0

Abstract

Background: Postoperative nausea and vomiting (PONV) is a common complication following surgery. Only a few risk factors have consistently been reported to be independent predictors for PONV.

Aim: To report Apfel scores for orthopedic patients then correlate these scores to the number of antiemetics prescribed and subsequently administered in both the perioperative and post operative setting and determine if screening for Apfel scores is beneficial to predict PONV.

Methods: A retrospective analysis of patients admitted under orthopedic units between 1st July 2020 and 31st July 2020 was conducted at a tertiary teaching hospital in Australia. Patients were screened and allocated an Apfel score and antiemetics agents prescribed and subsequently administered were recorded.

Results: A total of 115 patients were screened for inclusion. Of these 4 patients met this exclusion criteria, resulting in a total sample size of 111 patients. An Apfel score of 2 was reported in 45.0% of patients, followed by 28.8% of patients scoring 3, with 12.6% scoring one. Only 5.4% of patients scored the highest risk of 4, with 8.2% of patients with no Apfel score documented.

Conclusion: Orthopedic patients tend to score 2 or more in their Apfel score placing them at higher risk of postoperative nausea and/or vomiting according to the collectively validated Apfel's simplified risk score. There was no statistically significant relationship between the Apfel score and the number of antiemetic agents prescribed or administered from both the perioperative and post-operative setting following orthopedic surgery in this cohort of adult patients.

骨科手术中的止吐药和Apfel评分。
背景:术后恶心呕吐(PONV)是术后常见的并发症。只有少数风险因素一直被报道为PONV的独立预测因素。目的:报告骨科患者的Apfel评分,然后将这些评分与围手术期和术后开具和随后服用的止吐药数量相关联,并确定Apfel分数筛查是否有利于预测PONV。方法:对2020年7月1日至7月31日期间在澳大利亚一家三级教学医院入住骨科的患者进行回顾性分析。对患者进行筛查并分配Apfel评分,并记录处方和随后服用的止吐剂。结果:共有115名患者进行了入选筛查。在这4名患者中,符合这一排除标准,导致总样本量为111名患者。据报道,45.0%的患者Apfel评分为2,其次是28.8%的患者评分为3,12.6%的患者评分1。只有5.4%的患者评分最高,为4分,8.2%的患者没有Apfel评分记录。结论:根据经集体验证的Apfel简化风险评分,骨科患者的Apfel评分往往为2分或更多,这使他们术后恶心和/或呕吐的风险更高。在这组成年患者中,Apfel评分与骨科手术后围手术期和术后开具或服用的止吐剂数量之间没有统计学上的显著关系。
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来源期刊
Hospital Pharmacy
Hospital Pharmacy PHARMACOLOGY & PHARMACY-
CiteScore
1.70
自引率
0.00%
发文量
63
期刊介绍: Hospital Pharmacy is a monthly peer-reviewed journal that is read by pharmacists and other providers practicing in the inpatient and outpatient setting within hospitals, long-term care facilities, home care, and other health-system settings The Hospital Pharmacy Assistant Editor, Michael R. Cohen, RPh, MS, DSc, FASHP, is author of a Medication Error Report Analysis and founder of The Institute for Safe Medication Practices (ISMP), a nonprofit organization that provides education about adverse drug events and their prevention.
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