Potential use of Acrocomia aculeata Pulp Oil in the Modulation of Chronic Non-communicable Diseases, Especially in Diabetes: A Systematic Review.

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM

Current diabetes reviews Pub Date : 2024-01-01 DOI:10.2174/1573399820666230913105935

Maurílio de Souza Cazarim, Davi Trombini Aleixo, Estael Luzia Coelho da Cruz-Cazarim, Mohamed A Abd El-Salam, Frederico Pittella

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引用次数: 0

Abstract

Introduction: The fruit oil from Acrocomia aculeata (Macauba or Bocaiuva) is highly rich in antioxidants and other bioactive compounds, emerging as a natural source of high potential for the modulation of chronic non-communicable diseases (NCDs), like diabetes. Its effects on chronic NCDs are poorly studied yet. This review aimed to evaluate the therapeutic results of pharmaceutical preparations containing Acrocomia aculeata pulp oil that are used for chronic NCDs.

Method: A search was performed using PICO acronyms in English, Portuguese, and Spanish languages in the MEDLINE®, PubMed, EMBASE, Scopus, LILACs, and CENTRAL Cochrane Library databases. The degree of agreement for selection and eligibility was significant (Kappa= 0.992; 95% CI: 0.988-0.996). The difference between the intervention and control groups for blood glucose reduction was 63.5 ± 69.5 mg/dL (p<0.0001).

Result: Overall, an improvement percentage of 55.1 ± 0.1 was observed for the variables associated with chronic NCDs, which represented 89.96% of the relative risk reduction (efficacy).

Conclusion: The Acrocomia aculeate pulp oil exhibited promising results in experimental studies for glycemic control and reduction of a specific tumor, indicating a good potential to be explored for chronic NCDs treatment.

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Acrocomia aculeata果肉油在调节慢性非传染性疾病，尤其是糖尿病方面的潜在用途：系统综述。

简介：Acrocomia aculeata（Macauba 或 Bocaiuva）果实油富含抗氧化剂和其他生物活性化合物，是一种极具潜力的天然来源，可用于调节慢性非传染性疾病（NCD），如糖尿病。目前，人们对其对慢性非传染性疾病的影响还缺乏深入研究。本综述旨在评估含有刺五加果肉油的药物制剂对慢性非传染性疾病的治疗效果：方法：使用 PICO 首字母缩写词以英语、葡萄牙语和西班牙语在 MEDLINE®、PubMed、EMBASE、Scopus、LILACs 和 CENTRAL Cochrane 图书馆数据库中进行检索。选择和资格审查的一致程度非常高（Kappa= 0.992；95% CI：0.988-0.996）。干预组和对照组在降低血糖方面的差异为 63.5 ± 69.5 mg/dL（pResult：总体而言，慢性非传染性疾病相关变量的改善率为 55.1 ± 0.1，占相对风险降低率（疗效）的 89.96%：Acrocomia aculeate 纸浆油在控制血糖和减少特定肿瘤的实验研究中表现出良好的效果，表明其在治疗慢性非传染性疾病方面具有良好的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current diabetes reviews ENDOCRINOLOGY & METABOLISM-

CiteScore

6.30

自引率

0.00%

发文量

158

期刊介绍： Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.