Automatically Summarizing Evidence from Clinical Trials: A Prototype Highlighting Current Challenges.

Abstract

We present TrialsSummarizer, a system that aims to automatically summarize evidence presented in the set of randomized controlled trials most relevant to a given query. Building on prior work (Marshall et al., 2020), the system retrieves trial publications matching a query specifying a combination of condition, intervention(s), and outcome(s), and ranks these according to sample size and estimated study quality. The top-k such studies are passed through a neural multi-document summarization system, yielding a synopsis of these trials. We consider two architectures: A standard sequence-to-sequence model based on BART (Lewis et al., 2019), and a multi-headed architecture intended to provide greater transparency to end-users. Both models produce fluent and relevant summaries of evidence retrieved for queries, but their tendency to introduce unsupported statements render them inappropriate for use in this domain at present. The proposed architecture may help users verify outputs allowing users to trace generated tokens back to inputs. The demonstration video is available at: https://vimeo.com/735605060 The prototype, source code, and model weights are available at: https://sanjanaramprasad.github.io/trials-summarizer/.