The state of astragaloside IV research: A bibliometric and visualized analysis

IF 2.1 4区医学 Q3 PHARMACOLOGY & PHARMACY

Fundamental & Clinical Pharmacology Pub Date : 2023-09-12 DOI:10.1111/fcp.12956

Ning Liu, Yansu Ji, Rui Liu, Xin Jin

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引用次数: 0

Abstract

Background

Astragaloside IV has emerged as a pharmaceutical monomer with great medical applications and potential. Astragaloside IV has many effects such as improving myocardial ischemia, cerebral ischemia–reperfusion injury, anti-inflammatory, analgesic, antiviral, promoting lymphocyte proliferation, and antitumor effects. However, there are few bibliometric studies on astragaloside IV.

Objectives

We aim to visualize the hotspots and trends in astragaloside IV research through bibliometric analysis to further understand the future development of basic and clinical research.

Methods The articles and reviews on astragaloside IV were screened from the Web of Science Core Collection, and knowledge maps were generated using CiteSpace software. Bibliometric analysis was performed on 971 articles published from 1998 to 2022.

Results

The number of articles on astragaloside IV increased yearly. These publications came from 42 countries/regions, with China being the largest. The primary research institutions were Shanghai University of Traditional Chinese Medicine and Guangzhou University of Traditional Chinese Medicine. Journal of Ethnopharmacology was the most studied journal and co-cited journal. A total of 473 authors were included, among which Hongxin Wang had the highest number of publications and Zhang Wd had the highest total citation frequency. After analysis, the most common keywords are astragaloside IV, expression, and oxidative stress. Cardiovascular disease, cerebral ischemia, cancer, and kidney disease are current and developing research fields.

Conclusion

This study used bibliometrics and visualization methods to analyze the research hotspots and trends of astragaloside IV. Astragaloside IV on ischemia–reperfusion injury, cancer, and tumor may become the focus of future research.

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黄芪皂苷 IV 的研究现状：文献计量和可视化分析。

背景：黄芪皂苷 IV 是一种具有巨大医学应用价值和潜力的药物单体。黄芪皂苷 IV 具有改善心肌缺血、脑缺血再灌注损伤、抗炎、镇痛、抗病毒、促进淋巴细胞增殖、抗肿瘤等多种作用。然而，有关黄芪皂苷 IV 的文献计量学研究却很少：旨在通过文献计量学分析，直观了解黄芪皂苷 IV 的研究热点和趋势，从而进一步了解基础和临床研究的未来发展。方法从 Web of Science 核心数据库中筛选有关黄芪皂苷 IV 的文章和综述，并使用 CiteSpace 软件生成知识图谱。对1998年至2022年发表的971篇文章进行了文献计量分析：结果：有关黄芪皂苷 IV 的文章数量逐年增加。这些论文来自 42 个国家/地区，其中中国的论文数量最多。主要研究机构为上海中医药大学和广州中医药大学。民族药学杂志》是被研究最多的期刊，也是被联合引用最多的期刊。共收录了 473 位作者，其中王红新的论文数量最多，张文德的总被引频次最高。经过分析，最常见的关键词是黄芪皂苷 IV、表达和氧化应激。心血管疾病、脑缺血、癌症和肾脏疾病是当前正在发展的研究领域：本研究采用文献计量学和可视化方法分析了黄芪皂苷 IV 的研究热点和趋势。黄芪皂苷 IV 对缺血再灌注损伤、癌症和肿瘤的作用可能成为未来研究的重点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fundamental & Clinical Pharmacology 医学-药学

CiteScore

5.30

自引率

6.90%

发文量

111

审稿时长

6-12 weeks

期刊介绍： Fundamental & Clinical Pharmacology publishes reports describing important and novel developments in fundamental as well as clinical research relevant to drug therapy. Original articles, short communications and reviews are published on all aspects of experimental and clinical pharmacology including: Antimicrobial, Antiviral Agents Autonomic Pharmacology Cardiovascular Pharmacology Cellular Pharmacology Clinical Trials Endocrinopharmacology Gene Therapy Inflammation, Immunopharmacology Lipids, Atherosclerosis Liver and G-I Tract Pharmacology Metabolism, Pharmacokinetics Neuropharmacology Neuropsychopharmacology Oncopharmacology Pediatric Pharmacology Development Pharmacoeconomics Pharmacoepidemiology Pharmacogenetics, Pharmacogenomics Pharmacovigilance Pulmonary Pharmacology Receptors, Signal Transduction Renal Pharmacology Thrombosis and Hemostasis Toxicopharmacology Clinical research, including clinical studies and clinical trials, may cover disciplines such as pharmacokinetics, pharmacodynamics, pharmacovigilance, pharmacoepidemiology, pharmacogenomics and pharmacoeconomics. Basic research articles from fields such as physiology and molecular biology which contribute to an understanding of drug therapy are also welcomed.