[Risk factors and adherence to treatment of patients with cerebrovascular diseases].

Q3 Medicine
L I Pyshkina, A A Tyazhelnikov, A A Kabanov, D T Sherazadishvili, Z H Osmaeva, S V Prikazchikov, P R Kamchatnov
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引用次数: 0

Abstract

Objective: To assess the representation of risk factors and treatment adherence in patients with cerebrovascular diseases.

Material and methods: A single-stage cross-sectional non-comparable study was conducted, which included 492 patients, of whom 133 had an ischemic stroke/transient ischemic attack (main group, MG), 344 had chronic cerebrovascular pathology (comparison group, CG). The representation of risk factors, the state of cognitive functions, the severity of anxiety and depression were evaluated.

Results: MG respondents visit specialized specialists more often than CG (p<0.001), are more committed to taking antiplatelet agents (p<0.003), statins (p<0.005), antihypertensive drugs (p<0.005). Regular intake of antithrombotic drugs was associated with the history of ischemic stroke (r=0.483; p<0.01), type 2 diabetes (r=0.637; p<0.011), atrial fibrillation (r=0.481; p<0.001), living in a family (r=0.493; p<0.03). An inverse correlation was established between the systematic intake of antiplatelet drugs and the age of the respondents (r=-0.637; p<0.002), cognitive impairment (r=-0.433; p<0.05), the history of the gastrointestinal tract diseases (gastric ulcer and duodenal ulcer) (r=-0.563; p<0.001). Irregular medication intake was observed in patients aged over 60 years compared with younger (17.3% and 6.4%, respectively, p=0.001), patients living in a family compared with single (85.6% and 65.1%, p=0.032). The history of ischemic stroke or myocardial infarction is associated with increased adherence to regular medication.

Conclusion: The study of risk factors and the assessment of treatment adherence can ensure the formation of an effective strategy for primary and secondary prevention of cerebrovascular diseases.

[脑血管疾病患者的危险因素与治疗依从性]。
目的:评价脑血管病患者危险因素的表现及治疗依从性。材料与方法:采用单期横断面非可比性研究,纳入492例患者,其中缺血性卒中/短暂性脑缺血发作133例(主组,MG),慢性脑血管病变344例(对照组,CG)。评估危险因素的代表性、认知功能状态、焦虑和抑郁的严重程度。结果:MG受访者就诊专科次数多于CG受访者(ppppr=0.483;公关= 0.637;公关= 0.481;公关= 0.493;公关= -0.637;公关= -0.433;公关= -0.563;p=0.001),有家庭的患者与单身患者相比(85.6%和65.1%,p=0.032)。缺血性中风或心肌梗死的病史与增加对常规药物的依从性有关。结论:脑血管病危险因素的研究和治疗依从性的评价可以确保形成有效的脑血管病一级和二级预防策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Medicine-Psychiatry and Mental Health
CiteScore
0.80
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