Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?

IF 0.5 4区医学 Q4 SURGERY

Cirugia Y Cirujanos Pub Date : 2023-01-01 DOI:10.24875/CIRU.21000718

Jorge Martínez-Ulloa-Torres, Paulo Gutiérrez-Torres, Pablo Castro-Ruiz, Patricia B Bolado-García, Mariano Hernandez-Dominguez, Luis F Aguilar-Castillejos, Mauro E Tun-Abraham, Juan P Baas-Cruz

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引用次数: 0

Abstract

Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic.

Objective: The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic.

Material and methods: Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes.

Results: The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008).

Conclusion: The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.

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COVID时代肾移植等待名单死亡率:停止移植活动是否可取?

肾移植是治疗终末期肾病(ESRD)的首选方法。自2020年3月以来，由于COVID-19大流行，墨西哥的移植活动受到影响。目的:本研究的目的是确定Yucatán转诊医院因流感大流行而暂停活动对等待尸体供体肾移植的患者死亡率的影响。材料与方法:本院18岁以上肾移植候诊患者。在患者死亡的情况下，会调查原因，特别是与COVID-19有关的原因。所有分析均认为双尾p≤0.05具有显著性。结果:2020年WL中ESRD患者死于COVID-19的优势比(OR)为OR = 5.04 (95% CI: 1.65-7.14, p = 0.023)。在WL中死于ESRD并延迟随访的OR = 6.59 (95% CI: 2.7 ~ 16.28, p = 0.008)。结论:延迟随访并移植保留的ESRD患者死亡概率高于COVID-19死亡概率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cirugia Y Cirujanos 医学-外科

CiteScore

0.90

自引率

20.00%

发文量

207

审稿时长

6-12 weeks

期刊介绍： Cirugía y Cirujanoses exponente del desarrollo académico, científico, médico, quirúrgico y tecnológico en materia de salud en México y en el ámbito internacional. Es una revista bimestral, open access, revisada por pares, que publica en español y en inglés (traducido sin coste para los autores) artículos científicos originales, casos clínicos, artículos de revisión de interés general y cartas al editor. Los artículos se seleccionan y publican siguiendo un riguroso análisis, de acuerdo con los estándares internacionalmente aceptados. Sus espacios están abiertos a los académicos, así como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos.