3D self-assembled nanocarriers for drug delivery.

IF 3.4 2区 医学 Q2 PHARMACOLOGY & PHARMACY
Hossein Karballaei Mirzahosseini, Mojgan Sheikhi, Farhad Najmeddin, Mehrnoosh Shirangi, Mojtaba Mojtahedzadeh
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引用次数: 2

Abstract

There are many benefits to drug delivery from drug-carrier nanostructure systems. It might be developed to carefully control drug release rates or to deliver a precise amount of a therapeutic substance to particular body areas. Self-assembling is the process by which molecules and nanoparticles spontaneously organize into organized clusters. For instance, proteins and peptides can interact with one another to create highly organized supramolecular structures with various properties, such as helical ribbons and fibrous scaffolds. Another advantage of self-assembly is that it may be effective with a variety of materials, including metals, oxides, inorganic salts, polymers, semiconductors, and even organic semiconductors. Fullerene, graphene, and carbon nanotubes (CNTs), three of the most fundamental classes of three-dimensionally self-assembling nanostructured carbon-based materials, are essential for the development of modern nanotechnologies. Self-assembled nanomaterials are used in a variety of fields, including nanotechnology, imaging, and biosensors. This review study begins with a summary of various major 3D nanomaterials, including graphene oxide, CNTs, and nanodiamond, as well as 3D self-assembled polyfunctionalized nanostructures and adaptable nanocarriers for drug delivery.

用于药物递送的三维自组装纳米载体。
药物载体纳米结构系统对药物递送有许多好处。它可能被开发用于仔细控制药物释放率或将精确量的治疗物质输送到特定的身体区域。自组装是分子和纳米粒子自发组织成有组织簇的过程。例如,蛋白质和多肽可以相互作用,产生具有各种特性的高度组织化的超分子结构,如螺旋带和纤维支架。自组装的另一个优点是,它可以有效地与各种材料,包括金属,氧化物,无机盐,聚合物,半导体,甚至有机半导体。富勒烯、石墨烯和碳纳米管(CNTs)是三种最基本的三维自组装纳米结构碳基材料,对现代纳米技术的发展至关重要。自组装纳米材料被用于各种领域,包括纳米技术、成像和生物传感器。本综述首先概述了各种主要的3D纳米材料,包括氧化石墨烯、碳纳米管和纳米金刚石,以及用于药物递送的3D自组装多功能化纳米结构和适应性纳米载体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Drug Metabolism Reviews
Drug Metabolism Reviews 医学-药学
CiteScore
11.10
自引率
1.70%
发文量
21
审稿时长
1 months
期刊介绍: Drug Metabolism Reviews consistently provides critically needed reviews of an impressive array of drug metabolism research-covering established, new, and potential drugs; environmentally toxic chemicals; absorption; metabolism and excretion; and enzymology of all living species. Additionally, the journal offers new hypotheses of interest to diverse groups of medical professionals including pharmacologists, toxicologists, chemists, microbiologists, pharmacokineticists, immunologists, mass spectroscopists, as well as enzymologists working in xenobiotic biotransformation.
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