Clinical impact of C-reactive protein to albumin ratio of the 7th postoperative day on prognosis after laparoscopic colorectal cancer surgery.

IF 3 Q2 GASTROENTEROLOGY & HEPATOLOGY

Annals of Coloproctology Pub Date : 2023-08-01 DOI:10.3393/ac.2022.00234.0033

Masahiro Kataoka, Kuniyuki Gomi, Ken Ichioka, Takuya Iguchi, Tomoki Shirota, Arano Makino, Ko Shimada, Kiyotomi Maruyama, Motohiro Mihara, Shoji Kajikawa

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引用次数: 3

Abstract

Purpose: C-reactive protein to albumin ratio (CAR) has been utilized as a prognostic factor in various carcinomas. We investigated the relationship between preoperative, postoperative day (POD) 1, and POD 7 CARs and the prognosis of patients with colorectal cancer (CRC).

Methods: Three hundred twenty patients with CRC who underwent laparoscopic radical resection between May 2011 and December 2016 were enrolled. Patients were selected into 2 groups, high CAR and low CAR (n=72/group), based on preoperative, POD 1, and POD 7 CARs. The relapse-free survival (RFS) and overall survival (OS) were compared between groups using propensity score matching.

Results: The high CAR group had a significantly worse RFS (P<0.001) and OS (P=0.002) at POD 7 than those in the low CAR group. However, in preoperative and POD 1 analysis, no differences were observed.

Conclusion: In patients with CRC, CAR of POD 7 was a significant prognostic factor.

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腹腔镜结直肠癌术后第7天c反应蛋白/白蛋白比值对预后的影响

目的:c反应蛋白与白蛋白比率(CAR)已被用作多种癌症的预后因素。我们探讨了大肠癌(CRC)患者术前、术后一天(POD) 1和POD 7 CARs与预后的关系。方法:选取2011年5月至2016年12月行腹腔镜根治术的320例结直肠癌患者。根据术前、POD 1、POD 7 CARs分为高CAR组和低CAR组(n=72/组)。采用倾向评分匹配法比较各组无复发生存期(RFS)和总生存期(OS)。结论:在结直肠癌患者中，POD 7的CAR是一个重要的预后因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Coloproctology Multiple-

CiteScore

3.30

自引率

3.20%

发文量