Assessment of papillary muscle free strain in hypertrophic cardiomyopathy and hypertension-induced left ventricular hypertrophy.

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Journal of Africa Pub Date : 2023-07-23 Epub Date: 2023-02-27 DOI:10.5830/CVJA-2022-070

Cennet Yildiz, Atilla Koyuncu, Lutfi Ocal, Mustafa Ozan Gursoy, Ersan Oflar, Gokhan Kahveci

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引用次数: 0

Abstract

Objectives: We aimed to evaluate and compare papillary muscle free strain in hypertrophic cardiomyopathy (HCMP) and hypertensive (HT) patients.

Methods: Global longitudinal strain (GLS), and longitudinal myocardial strain of the anterolateral (ALPM) and posteromedial papillary muscles (PMPM) were obtained in 46 HCMP and 50 HT patients.

Results: Interventricular septum (IVS)/posterior wall (PW) thickness ratio, left ventricular mass index (LVMI), left atrial anteroposterior diameter (LAAP) and mitral E/E' were found to be increased in patients with HCMP compared to HT patients. Left ventricular cavity dimensions were smaller in HCMP patients. GLS of HCMP and HT patients were - 14.52 ± 3.01 and -16.85 ± 1.36%, respectively (p < 0.001). Likewise, ALPM and PMPM free strain values were significantly reduced in HCMP patients over HT patients [-14.00% (-22 to -11%) and -15.5% (-24.02 to -10.16%) vs -23.00% (-24.99 to -19.01%) and -22.30% (-26.48 to -15.95%) (p = 0.016 and p = 0.010)], respectively. ALPM free strain showed a statistically significant correlation with GLS, maximal wall thickness, IVS thickness and LVMI. PMPM free strain showed a significant correlation with GLS, IVS thickness and LAAP. The GLS value of - 13.05 had a sensitivity of 61.9% and a specificity of 97.4% for predicting HCMP. ALPM and PMPM free strain values of -15.31 and -17.17% had 63 and 76.9% sensitivity and 85.7 and 76.9% specificity for prediction of HCMP.

Conclusions: Besides other echocardiographic variables, which were investigated in earlier studies, papillary muscle free strain also could be used in HCMP to distinguish HCMP- from HT-associated hypertrophy.

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肥厚型心肌病和高血压诱导的左心室肥大中乳头肌游离应变的评估。

目的：我们旨在评估和比较肥厚型心肌病（HCMP）和高血压（HT）患者的乳头肌游离应变。方法：对46例HCMP和50例HT患者进行了整体纵向应变（GLS）、前外侧乳头肌（ALPM）和后内侧乳头肌（PMPM）的纵向心肌应变的测定。结果：与HT患者相比，HCMP患者的室间隔（IVS）/后壁（PW）厚度比、左心室质量指数（LVMI）、左心房前后径（LAAP）和二尖瓣E/E’均增加。HCMP患者的左心室腔尺寸较小。HCMP和HT患者的GLS分别为-14.52±3.01和-16.85±1.36%（p＜0.001）。同样，HCMP患者的ALPM和PMPM游离菌株值比HT患者显著降低[-14.00%（-22至-11%）和-15.5%（-24.02%至-10.16%）vs-23.00%（-24.99至-19.01%）和-22.30%（-26.48至-15.95%）（p＝0.016和p＝0.010）]。无ALPM菌株与GLS、最大壁厚、IVS厚度和LVMI呈统计学显著相关。无PMPM菌株与GLS、IVS厚度和LAAP显著相关。GLS值-13.05对预测HCMP的敏感性为61.9%，特异性为97.4%。ALPM和PMPM游离应变值分别为-15.31和-17.17%，对预测HCMP的敏感性分别为63和76.9%，特异性分别为85.7和76.9%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cardiovascular Journal of Africa CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.