HIV/AIDS Curability Study, Different Approaches and Drug Combination.

Q3 Pharmacology, Toxicology and Pharmaceutics

Infectious disorders drug targets Pub Date : 2023-01-01 DOI:10.2174/1871526523666230117115826

Da-Yong Lu, Ting-Ren Lu

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引用次数: 0

Abstract

Aim: HIV infection is currently an incurable disease characterized by life-long drug utility. Its incurable causality and mechanism are still unknown to us.

Methods: To overcome this therapeutic setback, some breakthroughs should be made by utilizing different approaches. How to plan some experimental and clinical novelty for HIV curability is a modern challenge. In this article, new ideas and approaches for global HIV/AIDS therapeutic strategies are proposed and represented by scientific insights.

Results: Pharmaceutical characteristics, herbal medicine, novel drug targets, cutting-edge biotherapy, drug combination, animal modalities, and immune-stimuli for HIV latency, as well as clearance, are highlighted.

Discussion: To elucidate our understanding of curative treatment for HIV/AIDS, many new pathological discoveries, expansion, technical advances, and potential drug targets are constructed. After the discovery of novel pathogenesis and therapeutic evolution, HIV/AIDS therapeutic curability may become achievable and a reality.

Conclusion: Transformation from animal model investigation to widespread therapies for larger volume of human population is a necessity in modern medicine. In this infectious treatment scenario, major breakthroughs in medicine and drug development are anticipated.

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HIV/AIDS的可治愈性研究，不同的治疗方法和药物组合。

目的:HIV感染是目前以终身药物效用为特征的不治之症。其不可治愈的因果关系和机制仍是未知的。方法:为了克服这一治疗挫折，应利用不同的途径取得一些突破。如何为艾滋病的可治愈性策划一些实验和临床创新是一个现代挑战。在本文中，提出了全球艾滋病治疗策略的新思路和新方法，并以科学见解为代表。结果:强调了药物特性，草药，新药物靶点，尖端生物疗法，药物联合，动物模式，HIV潜伏期和清除的免疫刺激。讨论:为了阐明我们对HIV/AIDS治愈性治疗的认识，许多新的病理发现、扩展、技术进步和潜在的药物靶点被构建。随着新的发病机制的发现和治疗方法的发展，HIV/AIDS的治疗治愈可能成为可能和现实。结论:现代医学必须从动物模型研究转向更大规模的广泛治疗。在这种感染治疗情况下，预计医学和药物开发将取得重大突破。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Infectious disorders drug targets Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

3.10

自引率

0.00%

发文量

123

期刊介绍： Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continues to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.