Incidence, risk factors, and clinical sequelae of incomplete stent apposition after sirolimus-eluting stent.

IF 1.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

International Journal of Cardiovascular Imaging Pub Date : 2023-10-01 Epub Date: 2023-07-08 DOI:10.1007/s10554-023-02896-w

Peng Liu, Chun-Guang Qiu, Zhen-Wen Huang, Yun Zhou

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引用次数: 1

Abstract

Incomplete stent apposition has been documented after sirolimus-eluting stent implantation. However, its clinical sequelae remain controversial. To identify the incidence and its clinical consequences of ISA, IVUS was performed on 78 patients. In spite of well apposition immediately after the deployment, late stent malapposition occurred after 6-months follow-up. A total of 7 patients who received SES showed ISA. There were no significant differences in IVUS measurements between patients with or without ISA. However, there was an increase in external elastic membrane area in ISA group than non-ISA group (19.69 ± 3.50 vs. 15.05 ± 2.56 mm², P<0.05). There were positive clinical events for ISA cases at 6-months clinical follow-up. Univariate and multivariable analyses indicated that hs-CRP, miR-21, and MMP-2 were risk factor for ISA. ISA was observed in 9% of patients after SES implantation, which was related to vessel positive remodeling. The incidence of MACEs in patients with ISA was higher than those without ISA. However, careful long-term follow-up remains to be clarified.

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西罗莫司洗脱支架后支架贴壁不完全的发生率、危险因素和临床后遗症。

西罗莫司洗脱支架植入术后，支架附着不完全。然而，其临床后遗症仍然存在争议。为了确定ISA的发生率及其临床后果，对78名患者进行了IVUS。尽管在部署后立即贴壁良好，但在6个月的随访后出现晚期支架贴壁不良。共有7名接受SES治疗的患者显示ISA。患有或不患有ISA的患者的IVUS测量结果没有显著差异。然而，ISA组的外弹性膜面积比非ISA组增加（19.69 ± 3.50对15.05 ± 2.56 mm2，P

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来源期刊

International Journal of Cardiovascular Imaging 医学-核医学

CiteScore

4.00

自引率

9.50%

发文量

审稿时长

1 months

期刊介绍： The International Journal of Cardiovascular Imaging publishes technical and clinical communications (original articles, review articles and editorial comments) associated with cardiovascular diseases. The technical communications include the research, development and evaluation of novel imaging methods in the various imaging domains. These domains include magnetic resonance imaging, computed tomography, X-ray imaging, intravascular imaging, and applications in nuclear cardiology and echocardiography, and any combination of these techniques. Of particular interest are topics in medical image processing and image-guided interventions. Clinical applications of such imaging techniques include improved diagnostic approaches, treatment , prognosis and follow-up of cardiovascular patients. Topics include: multi-center or larger individual studies dealing with risk stratification and imaging utilization, applications for better characterization of cardiovascular diseases, and assessment of the efficacy of new drugs and interventional devices.