Clinical Utility of Repetitive Nerve Stimulation Test in Differentiating Multifocal Motor Neuropathy From Progressive Muscular Atrophy.

Q3 Medicine

Journal of Clinical Neuromuscular Disease Pub Date : 2022-06-01 DOI:10.1097/CND.0000000000000401

Shunsuke Watanabe, Kenji Sekiguchi, Yoshikatsu Noda, Riki Matsumoto

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引用次数: 1

Abstract

Objectives: To evaluate the utility of repetitive nerve stimulation test (RNS) for differentiating multifocal motor neuropathy (MMN) and progressive muscular atrophy (PMA).

Methods: We retrospectively enrolled 20 patients with MMN or PMA. We extracted the results of the initial 3-Hz RNS in the ulnar and accessory nerves and compared the percentage and frequency of abnormal decremental responses between both groups.

Results: RNS was performed in 8 ulnar and 9 accessory nerves in patients with MMN, and in 8 ulnar and 10 accessory nerves in patients with PMA. Patients with MMN had a significantly lower decrement percentage (0.6 ± 4.0% in MMN vs. 10.3 ± 6.5% in PMA, P < 0.01) and frequency of abnormal decremental response (0 of 9 in MMN vs. 6 of 10 in PMA, P = 0.01) than patients with PMA in the accessory nerve.

Conclusions: The RNS has clinical utility for differentiating MMN from PMA.

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重复神经刺激试验鉴别多灶性运动神经病与进行性肌萎缩的临床应用。

目的:评价重复神经刺激试验(RNS)在鉴别多灶性运动神经病(MMN)和进行性肌萎缩症(PMA)中的应用价值。方法:回顾性研究20例MMN或PMA患者。我们提取尺神经和副神经的初始3-Hz RNS结果，比较两组之间异常递减反应的百分比和频率。结果:MMN患者行8根尺神经和9根副神经RNS, PMA患者行8根尺神经和10根副神经RNS。MMN患者的减量率(MMN为0.6±4.0%，PMA为10.3±6.5%，P < 0.01)和异常减量反应频率(MMN为0 / 9,PMA为6 / 10,P = 0.01)明显低于副神经PMA患者。结论:RNS在鉴别MMN和PMA方面具有临床应用价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Neuromuscular Disease Medicine-Medicine (all)

CiteScore

1.60

自引率

0.00%

发文量

期刊介绍： Journal of Clinical Neuromuscular Disease provides original articles of interest to physicians who treat patients with neuromuscular diseases, including disorders of the motor neuron, peripheral nerves, neuromuscular junction, muscle, and autonomic nervous system. Each issue highlights the most advanced and successful approaches to diagnosis, functional assessment, surgical intervention, pharmacologic treatment, rehabilitation, and more.