Updates in the diagnosis and management of coeliac disease

IF 3.2 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Mohamed G. Shiha , Stefania Chetcuti Zammit , Luca Elli , David S. Sanders , Reena Sidhu
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引用次数: 0

Abstract

Coeliac disease is a common autoimmune disorder induced by ingesting gluten, the protein component of wheat, barley, and rye. It is estimated that one-in-hundred people worldwide have coeliac disease, of whom the majority remain undiagnosed. Coeliac disease is characterized by a wide range of gastrointestinal and extraintestinal symptoms but can also present asymptomatically. Diagnosing coeliac disease depends on the concordance of clinical, serological and histopathological data. However, the diagnosis can be challenging and frequently overlooked. Undiagnosed coeliac disease is associated with an increased risk of complications and detrimental effects on quality of life. Early diagnosis and treatment of coeliac disease are necessary to reduce the risk of long-term complications.

乳糜泻诊断和治疗的最新进展
乳糜泻是一种常见的自身免疫性疾病,由摄入小麦、大麦和黑麦的蛋白质成分谷蛋白引起。据估计,全世界每一百人中就有一人患有腹腔疾病,其中大多数仍未确诊。乳糜泻的特点是有广泛的胃肠道和肠外症状,但也可以无症状出现。腹腔疾病的诊断取决于临床、血清学和组织病理学数据的一致性。然而,诊断可能具有挑战性,并且经常被忽视。未确诊的腹腔疾病会增加并发症的风险,并对生活质量产生不利影响。腹腔疾病的早期诊断和治疗对于降低长期并发症的风险是必要的。
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来源期刊
CiteScore
5.50
自引率
0.00%
发文量
23
审稿时长
69 days
期刊介绍: Each topic-based issue of Best Practice & Research Clinical Gastroenterology will provide a comprehensive review of current clinical practice and thinking within the specialty of gastroenterology.
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