The advantages of drinking mineral water in the rehabilitation of patients with viral hepatitis C with accompanying non-alcoholic fatty liver disease after suffering from COVID-19.

IF 1.3 4区 医学 Q4 ENVIRONMENTAL SCIENCES
Nataliya Dragomiretska, Iryna Zabolotna, Sergey Gushcha, Lidia Sierpińska, Ganna Izha, Alexander Plakida, Tetyana Bezverhnyuk
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引用次数: 1

Abstract

Introduction and objective: Past COVID-19 significantly worsens Chronic viral hepatitis C patients with concomitant NAFLD. The aim of the study was to assess effectiveness of including mineral water in the rehabilitation complex in patients with chronic hepatitis C with concomitant non-alcoholic fatty liver disease who contracted COVID-19.

Material and methods: 71 patients with chronic hepatitis C with concomitant NAFLD wo contracted COVID-19 were examined. Group I (control) - 39 patients prescribed dietary nutrition and exercise therapy. Group II (main) - 32 patients, in addition to the above, received packaged 'Shayanskaya' mineral water. Methodology comprised anamnestic, anthropometric and clinical, general clinical, biochemical, serological, and molecular genetic (markers of hepatitis C virus, HCV RNA PCR (qualitative and quantitative determination, genotyping), enzyme-linked immunosorbent assay, ultrasonographic examination of digestive organs, and statistical methods.

Results: Due to the treatment, there were significant improvements in carbohydrate and lipid metabolism, as well as the cytokine profile.

Conclusions: The effectiveness was established of the use of silicon low-mineralized bicarbonate sodium mineral water in the complex rehabilitation of patients with chronic hepatitis C and suputor NAFLD after contracted COVID-19. There was a significant improvement in the clinical course of the disease and improvement in the functional state of the liver.

饮用矿泉水对病毒性丙型肝炎合并非酒精性脂肪肝患者COVID-19后康复的优势
简介与目的:过去的COVID-19明显加重慢性病毒性丙型肝炎合并NAFLD患者。该研究的目的是评估在感染COVID-19的慢性丙型肝炎合并非酒精性脂肪肝患者的康复复康中加入矿泉水的有效性。材料与方法:对71例慢性丙型肝炎合并NAFLD合并COVID-19患者进行检查。第一组(对照组):39例患者接受饮食营养和运动治疗。II组(主要)- 32名患者,除上述外,还接受了包装的“Shayanskaya”矿泉水。方法包括记忆学、人体测量学和临床、一般临床、生化、血清学和分子遗传学(丙型肝炎病毒标记物、HCV RNA PCR(定性和定量测定、基因分型)、酶联免疫吸附试验、消化器官超声检查和统计学方法。结果:由于治疗,有显著改善碳水化合物和脂质代谢,以及细胞因子谱。结论:低矿化碳酸氢钠硅矿泉水在新型冠状病毒感染后慢性丙型肝炎合并继发NAFLD患者复杂康复治疗中的有效性得到证实。临床病程有明显改善,肝脏功能状态也有明显改善。
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来源期刊
Annals of Agricultural and Environmental Medicine
Annals of Agricultural and Environmental Medicine 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.00
自引率
5.90%
发文量
58
审稿时长
4-8 weeks
期刊介绍: All papers within the scope indicated by the following sections of the journal may be submitted: Biological agents posing occupational risk in agriculture, forestry, food industry and wood industry and diseases caused by these agents (zoonoses, allergic and immunotoxic diseases). Health effects of chemical pollutants in agricultural areas , including occupational and non-occupational effects of agricultural chemicals (pesticides, fertilizers) and effects of industrial disposal (heavy metals, sulphur, etc.) contaminating the atmosphere, soil and water. Exposure to physical hazards associated with the use of machinery in agriculture and forestry: noise, vibration, dust. Prevention of occupational diseases in agriculture, forestry, food industry and wood industry. Work-related accidents and injuries in agriculture, forestry, food industry and wood industry: incidence, causes, social aspects and prevention. State of the health of rural communities depending on various factors: social factors, accessibility of medical care, etc.
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