Primary esophageal melanoma: a case report.

IF 1 Q4 ONCOLOGY

Melanoma Management Pub Date : 2022-12-01 DOI:10.2217/mmt-2022-0002

Pooja Patel, Colton Boudreau, Samuel Jessula, Madelaine Plourde

引用次数: 0

Abstract

Primary esophageal melanoma remains a rare entity with less than 350 case reports noted in the current literature. This diagnosis is associated with a poor prognosis and early detection and management remains fundamental. In this report, we examine the case of an 80-year-old female who presented with a 1-year course of progressive dysphagia and weight loss. Investigations revealed a primary esophageal melanoma with no evidence of metastases. Pathology did not identify any targetable markers for systematic therapy and thus the patient successfully underwent a minimally invasive esophagectomy. Her postoperative course involved endoscopic esophageal dilatations due to an anastomotic stricture, as well as primary lung adenocarcinoma treated with radiotherapy but has otherwise remained without evidence of melanoma recurrence after 25 months from her surgery.

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原发性食管黑色素瘤1例报告。

原发性食道黑色素瘤仍然是一种罕见的实体，在目前的文献中只有不到350例报告。这种诊断与预后不良有关，早期发现和管理仍然是基本的。在本报告中，我们研究了一位80岁的女性，她出现了1年的进行性吞咽困难和体重减轻的过程。调查显示原发性食道黑色素瘤，无转移迹象。病理未发现任何系统治疗的靶向标记物，因此患者成功接受了微创食管切除术。由于吻合口狭窄，她的术后过程包括内镜下食管扩张，以及放疗治疗的原发性肺腺癌，但在手术后25个月仍无黑色素瘤复发的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Melanoma Management ONCOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

13 weeks

期刊介绍： Skin cancer is on the rise. According to the World Health Organization, 132,000 melanoma skin cancers occur globally each year. While early-stage melanoma is usually relatively easy to treat, once disease spreads prognosis worsens considerably. Therefore, research into combating advanced-stage melanoma is a high priority. New and emerging therapies, such as monoclonal antibodies, B-RAF and KIT inhibitors, antiangiogenic agents and novel chemotherapy approaches hold promise for prolonging survival, but the search for a cure is ongoing. Melanoma Management publishes high-quality peer-reviewed articles on all aspects of melanoma, from prevention to diagnosis and from treatment of early-stage disease to late-stage melanoma and metastasis. The journal presents the latest research findings in melanoma research and treatment, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. Key topics covered include: Risk factors, prevention and sun safety education Diagnosis, staging and grading Surgical excision of melanoma lesions Sentinel lymph node biopsy Biological therapies, including immunotherapy and vaccination Novel chemotherapy options Treatment of metastasis Prevention of recurrence Patient care and quality of life.