Role of Cardiac Biomarkers in Monitoring Cardiotoxicity in Chemotherapy Patients.

Q3 Medicine

Critical Pathways in Cardiology Pub Date : 2023-09-01 Epub Date: 2023-02-17 DOI:10.1097/HPC.0000000000000314

Ayman Battisha, Khalid Sawalha, Yasin Obeidat, Brijesh Patel

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引用次数: 0

Abstract

Purpose: This review aims to highlight the different types of chemotherapy-induced cardiotoxicity and will discuss the evidence base behind the use of different cardiac biomarkers to predict cardiovascular complications. Additionally, we will review the use of cardiac biomarkers to monitor cardiac outcomes and the role of cardioprotective medications in reducing cardiovascular side effects.

Recent findings: Chemotherapy has been linked to an increased risk of cardiotoxicity and heart failure. Currently, patients receiving chemotherapy undergo echocardiogram before starting chemotherapy and every 6 months to monitor for any decline in cardiac function. We reviewed the current evidence and practice guidelines of monitoring chemotherapy cardiotoxicity.

Summary: Cardio-oncology is a rapidly evolving subspecialty in cardiology, especially with the advent of new chemotherapeutic agents, which have cardiovascular side effects. Early detection of these effects is crucial to prevent life-threatening and irreversible cardiovascular outcomes. Monitoring troponin, pro-brain natriuretic peptide, and other cardiac biomarkers during chemotherapy will help to early detect cardiotoxicity.

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心脏生物标志物在监测化疗患者心脏毒性中的作用。

目的：本综述旨在强调不同类型的化疗诱导的心脏毒性，并将讨论使用不同的心脏生物标志物预测心血管并发症背后的证据基础。此外，我们将回顾心脏生物标志物用于监测心脏结果的使用，以及心脏保护药物在减少心血管副作用中的作用。最近的发现：化疗与心脏毒性和心力衰竭的风险增加有关。目前，接受化疗的患者在开始化疗前和每6个月进行一次超声心动图检查，以监测心脏功能的任何下降。我们回顾了目前监测化疗心脏毒性的证据和实践指南。摘要：心脏肿瘤学是心脏病学中一个快速发展的亚专业，尤其是随着新型化疗药物的出现，这些药物会产生心血管副作用。早期发现这些影响对于预防危及生命和不可逆转的心血管后果至关重要。在化疗期间监测肌钙蛋白、促脑钠肽和其他心脏生物标志物将有助于早期发现心脏毒性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Critical Pathways in Cardiology Medicine-Medicine (all)

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Critical Pathways in Cardiology provides a single source for the diagnostic and therapeutic protocols in use at hospitals worldwide for patients with cardiac disorders. The Journal presents critical pathways for specific diagnoses—complete with evidence-based rationales—and also publishes studies of these protocols" effectiveness.