Performance evaluation of Monaco radiotherapy treatment planning system using CIRS Thorax Phantom: Dosimetric assessment of flattened and non-flattened photon beams.

IF 1.4 4区 医学 Q4 ONCOLOGY
Amit Saini, Teerthraj Verma, V P Pandey, Avtar Singh, Pankaj Kumar
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Abstract

Aim: The present study was undertaken to evaluate the performance of different algorithms for flattening filter-free (FFF) and flattened (FF) photon beams in three different in-homogeneities.

Materials and method: Computed tomography (CT) image sets of the CIRS phantom maintained in the SAD setup by placing the ionization chamber in the lung, bone, and tissue regions, respectively, were acquired. The treatment planning system (TPS) calculated and the ionization chamber measured the doses at the center of the chamber (in the three mediums) were recorded for the flattened and non-flattened photon beams.

Results: The results were reported for photon energies of 6 MV, 10 MV, 15 MV, 6 FFF, and 10 FFF of field sizes 5 × 5 cm2, 10 × 10 cm2, and 15 × 15 cm2. In the bone inhomogeneity, the pencil beam algorithm predicted that the maximum dose variation was 4.88% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm2. In water inhomogeneity, both the collapsed cone and Monte Carlo algorithm predicted that the maximum dose variation was ± 3% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm2 and in 10-MV FFF photon energy for the field size 5 × 5 cm2, whereas in lung inhomogeneity, the pencil beam algorithm predicted that the highest dose variation was - 6.9% of measured chamber dose in 10-MV FFF photon energy for the field size 5 × 5 cm2.

Conclusion: FF and FFF beams performed differently in lung, water, and bone mediums. The assessment of algorithms was conducted using the anthropomorphic phantom; therefore, these findings may help in the selection of appropriate algorithms for particular clinical settings in radiation delivery.

使用CIRS Thorax Phantom的摩纳哥放射治疗计划系统的性能评估:平坦和非平坦光子束的剂量评估。
目的:本研究旨在评估不同算法在三种不同的非均匀性中对无滤波器(FFF)和平坦化(FF)光子束进行平坦化的性能。材料和方法:通过分别在肺、骨和组织区域放置电离室,获得在SAD设置中保持的CIRS体模的计算机断层扫描(CT)图像集。计算的治疗计划系统(TPS)和电离室测量的电离室中心(在三种介质中)的剂量记录了扁平和非扁平光子束的剂量。结果:报道了场大小为5×5 cm2、10×10 cm2和15×15 cm2的6MV、10MV、15MV、6FFF和10FFF的光子能量的结果。在骨不均匀性中,铅笔束算法预测,对于10×10cm2的场,在10-MV光子能量中,最大剂量变化为测量室剂量的4.88%。在水的不均匀性中,坍缩锥和蒙特卡罗算法都预测,对于10×10 cm2的场,在10-MV光子能量和5×5 cm2的场的10-MV FFF光子能量中,最大剂量变化为测量室剂量的±3%,而在肺的不均匀度中,铅笔束算法预测,在5×5cm2的场大小下,10-MV FFF光子能量的最高剂量变化为测量室剂量的-6.9%。结论:FF和FFF束在肺、水和骨介质中的表现不同。算法的评估是使用拟人体模进行的;因此,这些发现可能有助于为辐射输送的特定临床环境选择合适的算法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.80
自引率
15.40%
发文量
299
审稿时长
6 months
期刊介绍: The journal will cover technical and clinical studies related to health, ethical and social issues in field of Medical oncology, radiation oncology, medical imaging, radiation protection, non-ionising radiation, radiobiology. Articles with clinical interest and implications will be given preference.
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