Physical Exercise Interventions on Quality of Life in Parkinson Disease: A Network Meta-analysis.

IF 2.6 3区医学 Q2 CLINICAL NEUROLOGY

Journal of Neurologic Physical Therapy Pub Date : 2023-04-01 DOI:10.1097/NPT.0000000000000414

Patricia Lorenzo-García, Sergio Núñez de Arenas-Arroyo, Iván Cavero-Redondo, María José Guzmán-Pavón, Susana Priego-Jiménez, Celia Álvarez-Bueno

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引用次数: 0

Abstract

Background and purpose: Physical exercise is considered an effective intervention for maintaining or improving quality of life (QoL) in patients with Parkinson disease (PD), but there is no evidence showing which type of physical exercise intervention has more positive effects. This systematic review and meta-analysis aimed to synthesize the evidence regarding the effectiveness of exercise interventions on improving QoL in patients with PD, comparing different types of exercise interventions.

Methods: A literature search was conducted through January 2022. The methodological quality of the trials was assessed using the Cochrane risk of bias tool RoB2. For the meta-analysis, physical exercise interventions were classified into 5 training categories: resistance, endurance, alternative exercises, dance, and sensorimotor interventions. A standard meta-analysis and network meta-analysis were carried out to evaluate the efficacy of the different types of physical exercise interventions.

Results: The search retrieved 2451 studies, 48 of which were included in this network meta-analysis with a total of 2977 patients with PD. The indirect effects of the network meta-analysis showed positive results for alternative exercises (-0.46; 95% confidence interval [CI]: -0.76, -0.16), dance (-0.63; 95% CI: -1.08, -0.17), and sensorimotor interventions (-0.23; 95% CI: -0.40, -0.07) versus control comparisons.

Discussion and conclusions: More research is needed to determine the types of physical exercise interventions that are most beneficial and for which conditions of the disease they have the most positive effects.Video Abstract available for more insights from the authors (see the Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A398 ).

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体育锻炼干预对帕金森病患者生活质量的影响:网络meta分析

背景与目的:体育锻炼被认为是维持或改善帕金森病(PD)患者生活质量(QoL)的有效干预措施，但目前尚无证据表明哪一种体育锻炼干预措施的积极作用更大。本系统综述和荟萃分析旨在综合运动干预对改善PD患者生活质量的有效性的证据，比较不同类型的运动干预。方法:文献检索至2022年1月。使用Cochrane风险偏倚工具RoB2评估试验的方法学质量。在荟萃分析中，体育锻炼干预被分为5个训练类别:阻力、耐力、替代运动、舞蹈和感觉运动干预。采用标准荟萃分析和网络荟萃分析对不同类型体育锻炼干预的效果进行评价。结果:检索到2451项研究，其中48项纳入该网络荟萃分析，共2977例PD患者。网络meta分析的间接效应显示，替代运动的结果为正(-0.46;95%置信区间[CI]: -0.76， -0.16)，舞蹈(-0.63;95% CI: -1.08， -0.17)，感觉运动干预(-0.23;95% CI: -0.40， -0.07)。讨论和结论:需要更多的研究来确定最有益的体育锻炼干预类型，以及对哪种疾病有最积极的影响。视频摘要可获得作者的更多见解(参见视频，补充数字内容1,http://links.lww.com/JNPT/A398)。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neurologic Physical Therapy CLINICAL NEUROLOGY-REHABILITATION

CiteScore

5.70

自引率

2.60%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Neurologic Physical Therapy (JNPT) is an indexed resource for dissemination of research-based evidence related to neurologic physical therapy intervention. High standards of quality are maintained through a rigorous, double-blinded, peer-review process and adherence to standards recommended by the International Committee of Medical Journal Editors. With an international editorial board made up of preeminent researchers and clinicians, JNPT publishes articles of global relevance for examination, evaluation, prognosis, intervention, and outcomes for individuals with movement deficits due to neurologic conditions. Through systematic reviews, research articles, case studies, and clinical perspectives, JNPT promotes the integration of evidence into theory, education, research, and practice of neurologic physical therapy, spanning the continuum from pathophysiology to societal participation.