Challenges and opportunities in building a health economic framework for personalized medicine in oncology.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-09-01 Epub Date: 2023-08-21 DOI:10.2217/pme-2022-0008

Pedro Nazareth Aguiar, Silvio Matsas, Rodrigo Dienstmann, Carlos Gil Ferreira

引用次数: 0

Abstract

Personalized medicine has allowed for knowledge at an individual level for several diseases and this has led to improvements in prevention and treatment of various types of neoplasms. Despite the greater availability of tests, the costs of genomic testing and targeted therapies are still high for most patients, especially in low- and middle-income countries. Although value frameworks and health technology assessment are fundamental to allow decision-making by policymakers, there are several concerns in terms of personalized medicine pharmacoeconomics. A global effort may improve these tools in order to allow access to personalized medicine for an increasing number of patients with cancer.

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建立肿瘤学个性化医学的健康经济框架的挑战和机遇。

个性化医学使人们能够在个人层面上了解几种疾病，从而改善了各种类型肿瘤的预防和治疗。尽管检测的可用性更高，但对大多数患者来说，基因组检测和靶向治疗的成本仍然很高，尤其是在中低收入国家。尽管价值框架和健康技术评估是决策者决策的基础，但在个性化药物药物经济学方面存在一些问题。全球努力可能会改进这些工具，以便为越来越多的癌症患者提供个性化药物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.