Improvements in Air Quality and Health Outcomes Among California Medicaid Enrollees Due to Goods Movement Actions.

Y-Y Meng, J G Su, X Chen, J Molitor, D Yue, M Jerrett
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These actions aimed to reduce total statewide domestic GM emissions to 2001 levels or lower by the year 2010; to reduce the statewide diesel particulate matter (DPM) health risk from GM by 85% by the year 2020; and to reduce the nitrogen oxides (NO<sub>x</sub>) emissions from international GM in the South Coast Air Basin by 30% from projected 2015 levels and 50% from projected 2020 levels. The years 2006 and 2007 marked an important milestone in starting to regulate GM polluters and adopting stricter standards for traffic-related air pollution.</p><p><p>This project aimed to examine the impact of the GM policy actions on reductions in ambient air pollution and subsequent improvements in health outcomes of Medi-Cal fee-for-service (FFS) beneficiaries with chronic conditions in 10 counties in California. Specifically, we examined whether the GM policy actions reduced air pollution near GMC corridors more than in control areas. We subsequently assessed whether there were greater decreases in emergency room (ER) visits and hospitalizations for enrollees with chronic conditions who lived in the GM corridors (GMCs) than for those who lived in other areas.</p><p><strong>Methods: </strong>The study used a quasi-experimental design. We defined areas within 500 m of truck-permitted freeways and ports as GMCs. We further defined non-goods movement corridors (NGMCs) as locations within 500 m of truck-prohibited freeways or 300 m of a connecting roadway, and areas out of GMCs and NGMCs as controls (CTRLs). We defined years 2004-2007 as the pre-policy period and years 2008-2010 as the post-policy period. We developed linear mixed-effects land use regression models and created annual air pollution surfaces for nitrogen dioxide (NO<sub>2</sub>), fine particulate matter (PM<sub>2.5</sub>), and ozone (O<sub>3</sub>) across California for years 2004-2010 at a spatial resolution of 30 m, then assigned them to enrollees' home addresses.</p><p><p>We used a retrospective cohort of 23,000 California Medicaid (Medi-Cal) FFS adult beneficiaries living in 10 California counties with six years of data (September 1, 2004, to August 31, 2010). Cohort beneficiaries had at least one of four chronic conditions, including asthma, chronic obstructive pulmonary disease (COPD), diabetes, and heart disease.</p><p><p>We used a difference-in-differences (DiD) model to assess whether air pollutant concentration and health care utilization (ER visits and hospitalizations) for cohort beneficiaries declined more for those living in intervention corridors (GMCs, NGMCs) than those living in CTRLs. All the models controlled for age, sex, language spoken, race/ethnicity, number of comorbidities in baseline years, county, time-varying health indicator variables, and several neighborhood variables.</p><p><p>To facilitate interpretation, we calculated the DiD estimates in each of the three years after the policy intervention. The DiD was used to assess the causal impact of regulatory policy on reductions of air pollution, as well as for the improvements in health outcomes.</p><p><p>We explored whether improvements in health outcomes were due to the air pollution reduction by using a multi- level mediation model, in which the effect of GM actions on health outcomes was mediated through the effect of actual air pollution reductions in the post-policy years. We used the Generalized Structural Equation Models for the estimation and combined the effects of NO<sub>2</sub> and PM<sub>2.5</sub> in the model. To further verify the causal inferences of the GM actions on reductions of exposures and improvements in health outcomes, we performed sensitivity analyses with propensity score weighting.</p><p><strong>Results: </strong>We observed statistically significant reductions in pollutant NO<sub>2</sub> and PM<sub>2.5</sub> concentrations for enrollees in all 10 counties. The enrollees in GMCs experienced greater reductions in NO<sub>2</sub> and PM<sub>2.5</sub> from the pre- to the post-policy periods than those in CTRLs. Greater reductions were also observed among beneficiaries living in NGMCs versus those in CTRLs, but those reductions were smaller than among beneficiaries living in GMCs. For O<sub>3</sub> concentrations, an opposite trend was observed.</p><p><p>Furthermore, we observed significantly greater reductions in ER visits for patients with asthma and COPD living in GMCs than those in CTRLS in the post-policy years. For example, we saw in the DiD modeling results there were 170 fewer ER visits for 1,000 beneficiaries with asthma per year in GMCs if the regionwide trend in the CTRL group was considered not related to the GM policy. Similarly, among the beneficiaries with COPD, there were 180 fewer ER visits per 1,000 patients estimated in the GMCs for the third year after the implementation of the policy.</p><p><p>We also observed greater reductions in ER visits among those with asthma, when comparing NGMCs with CTRLs, but reductions were smaller than comparisons between GMCs and CTRLs. The ER visits for those with COPD, diabetes, and the total sample in NGMCs also had downward trends in the post-policy year in comparison with those in CTRLs but the differences were not statistically significant; similar phenomena were also observed for the ER visits among those with diabetes and heart diseases and in the total sample when GMCs versus CTRLs and GMCs versus NGMCs were compared. Although hospitalizations also decreased more in GMCs than in NGMCs and more in NGMCs than in CTRLs in the post-policy period, results were not statistically significant.</p><p><p>Using the mediation models, we observed 0.129 more reductions in the expected number of ER visits among individuals with asthma for a composite reduction in one unit NO<sub>2</sub> and one unit PM<sub>2.5</sub> (DiD = -0.129, <i>P</i> < 0.05) from the pre-policy years to the post-policy years. The reductions in NO<sub>2</sub> and PM<sub>2.5</sub> due to policy change estimated by the mediation model are essentially the same as shown in the respective DiD models. Mediation analyses suggested that the effects of GM policy interventions on health improvements were largely due to exposure reductions. Finally, sensitivity analyses with propensity scores produced similar DiD results.</p><p><strong>Conclusions: </strong>This project has produced empirical evidence that air pollution control actions reduced pollution exposures among disadvantaged and susceptible populations. More importantly, our findings suggest that the reductions in air pollution led to health outcome improvements among low-income people with chronic conditions. Our investigation also contributed to scientific methods for assessing the health effects of long-term, large-scale, and complex regulatory actions with routinely collected pollutants and medical claims data. Therefore, the results strongly support both short-term and long-term efforts to improve air quality for all members of society and future studies on the impact of air pollution control policies.</p>","PeriodicalId":74687,"journal":{"name":"Research report (Health Effects Institute)","volume":" 205","pages":"1-61"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314313/pdf/hei-2021-205.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research report (Health Effects Institute)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: In 2006, the California Air Resources Board (CARB) and local air quality management districts implemented an Emission Reduction Plan for Ports and Goods Movement program (referred to hereinafter as GM policy actions) (CARB 2006). The GM policy actions comprise approximately 200 actions with an estimated investment value of $6 to $10 billion. These actions targeted the major sources and polluters related to goods movements, such as highways; ports and railyard trucks; ship fuel and shore power; cargo equipment; and locomotives. These actions aimed to reduce total statewide domestic GM emissions to 2001 levels or lower by the year 2010; to reduce the statewide diesel particulate matter (DPM) health risk from GM by 85% by the year 2020; and to reduce the nitrogen oxides (NOx) emissions from international GM in the South Coast Air Basin by 30% from projected 2015 levels and 50% from projected 2020 levels. The years 2006 and 2007 marked an important milestone in starting to regulate GM polluters and adopting stricter standards for traffic-related air pollution.

This project aimed to examine the impact of the GM policy actions on reductions in ambient air pollution and subsequent improvements in health outcomes of Medi-Cal fee-for-service (FFS) beneficiaries with chronic conditions in 10 counties in California. Specifically, we examined whether the GM policy actions reduced air pollution near GMC corridors more than in control areas. We subsequently assessed whether there were greater decreases in emergency room (ER) visits and hospitalizations for enrollees with chronic conditions who lived in the GM corridors (GMCs) than for those who lived in other areas.

Methods: The study used a quasi-experimental design. We defined areas within 500 m of truck-permitted freeways and ports as GMCs. We further defined non-goods movement corridors (NGMCs) as locations within 500 m of truck-prohibited freeways or 300 m of a connecting roadway, and areas out of GMCs and NGMCs as controls (CTRLs). We defined years 2004-2007 as the pre-policy period and years 2008-2010 as the post-policy period. We developed linear mixed-effects land use regression models and created annual air pollution surfaces for nitrogen dioxide (NO2), fine particulate matter (PM2.5), and ozone (O3) across California for years 2004-2010 at a spatial resolution of 30 m, then assigned them to enrollees' home addresses.

We used a retrospective cohort of 23,000 California Medicaid (Medi-Cal) FFS adult beneficiaries living in 10 California counties with six years of data (September 1, 2004, to August 31, 2010). Cohort beneficiaries had at least one of four chronic conditions, including asthma, chronic obstructive pulmonary disease (COPD), diabetes, and heart disease.

We used a difference-in-differences (DiD) model to assess whether air pollutant concentration and health care utilization (ER visits and hospitalizations) for cohort beneficiaries declined more for those living in intervention corridors (GMCs, NGMCs) than those living in CTRLs. All the models controlled for age, sex, language spoken, race/ethnicity, number of comorbidities in baseline years, county, time-varying health indicator variables, and several neighborhood variables.

To facilitate interpretation, we calculated the DiD estimates in each of the three years after the policy intervention. The DiD was used to assess the causal impact of regulatory policy on reductions of air pollution, as well as for the improvements in health outcomes.

We explored whether improvements in health outcomes were due to the air pollution reduction by using a multi- level mediation model, in which the effect of GM actions on health outcomes was mediated through the effect of actual air pollution reductions in the post-policy years. We used the Generalized Structural Equation Models for the estimation and combined the effects of NO2 and PM2.5 in the model. To further verify the causal inferences of the GM actions on reductions of exposures and improvements in health outcomes, we performed sensitivity analyses with propensity score weighting.

Results: We observed statistically significant reductions in pollutant NO2 and PM2.5 concentrations for enrollees in all 10 counties. The enrollees in GMCs experienced greater reductions in NO2 and PM2.5 from the pre- to the post-policy periods than those in CTRLs. Greater reductions were also observed among beneficiaries living in NGMCs versus those in CTRLs, but those reductions were smaller than among beneficiaries living in GMCs. For O3 concentrations, an opposite trend was observed.

Furthermore, we observed significantly greater reductions in ER visits for patients with asthma and COPD living in GMCs than those in CTRLS in the post-policy years. For example, we saw in the DiD modeling results there were 170 fewer ER visits for 1,000 beneficiaries with asthma per year in GMCs if the regionwide trend in the CTRL group was considered not related to the GM policy. Similarly, among the beneficiaries with COPD, there were 180 fewer ER visits per 1,000 patients estimated in the GMCs for the third year after the implementation of the policy.

We also observed greater reductions in ER visits among those with asthma, when comparing NGMCs with CTRLs, but reductions were smaller than comparisons between GMCs and CTRLs. The ER visits for those with COPD, diabetes, and the total sample in NGMCs also had downward trends in the post-policy year in comparison with those in CTRLs but the differences were not statistically significant; similar phenomena were also observed for the ER visits among those with diabetes and heart diseases and in the total sample when GMCs versus CTRLs and GMCs versus NGMCs were compared. Although hospitalizations also decreased more in GMCs than in NGMCs and more in NGMCs than in CTRLs in the post-policy period, results were not statistically significant.

Using the mediation models, we observed 0.129 more reductions in the expected number of ER visits among individuals with asthma for a composite reduction in one unit NO2 and one unit PM2.5 (DiD = -0.129, P < 0.05) from the pre-policy years to the post-policy years. The reductions in NO2 and PM2.5 due to policy change estimated by the mediation model are essentially the same as shown in the respective DiD models. Mediation analyses suggested that the effects of GM policy interventions on health improvements were largely due to exposure reductions. Finally, sensitivity analyses with propensity scores produced similar DiD results.

Conclusions: This project has produced empirical evidence that air pollution control actions reduced pollution exposures among disadvantaged and susceptible populations. More importantly, our findings suggest that the reductions in air pollution led to health outcome improvements among low-income people with chronic conditions. Our investigation also contributed to scientific methods for assessing the health effects of long-term, large-scale, and complex regulatory actions with routinely collected pollutants and medical claims data. Therefore, the results strongly support both short-term and long-term efforts to improve air quality for all members of society and future studies on the impact of air pollution control policies.

货物移动行动对加州医疗补助参保人空气质量和健康结果的改善。
2006年,加州空气资源委员会(CARB)和当地空气质量管理区实施了一项港口和货物运输减排计划(以下简称通用汽车政策行动)(CARB 2006)。通用汽车政策行动包括约200项行动,估计投资价值为60亿至100亿美元。这些行动的目标是与货物运输有关的主要来源和污染者,例如公路;港口和铁路车辆;船用燃料和岸电;货物设备;和机车。这些行动的目的是到2010年将全州范围内的转基因排放总量减少到2001年或更低的水平;到2020年,将全州范围内来自转基因汽车的柴油颗粒物(DPM)健康风险降低85%;并将南海岸空气盆地国际通用汽车的氮氧化物(NOx)排放量从2015年的预计水平减少30%,从2020年的预计水平减少50%。2006年和2007年是开始管制转基因污染者和对交通相关空气污染采取更严格标准的重要里程碑。本项目旨在审查转基因政策行动对减少环境空气污染的影响,并随后改善加州10个县的慢性病医疗-加州按服务收费(FFS)受益人的健康状况。具体来说,我们研究了转基因政策行动是否比控制区更能减少转基因走廊附近的空气污染。我们随后评估了居住在GM走廊(gmc)的慢性病患者的急诊室(ER)就诊和住院率是否比居住在其他地区的患者更低。方法:采用准实验设计。我们将允许卡车通行的高速公路和港口500米范围内的区域定义为gmc。我们进一步将非货物运输走廊(NGMCs)定义为距离禁止卡车通行的高速公路500米或连接道路300米范围内的位置,并将GMCs和NGMCs之外的区域定义为控制区(ctrl)。我们将2004-2007年定义为政策前时期,将2008-2010年定义为政策后时期。我们开发了线性混合效应土地利用回归模型,并以30米的空间分辨率创建了2004-2010年加州各地二氧化氮(NO2)、细颗粒物(PM2.5)和臭氧(O3)的年度空气污染面,然后将它们分配给参选者的家庭住址。我们采用了一项回顾性队列研究,研究对象为生活在加州10个县的23,000名加州医疗补助(Medi-Cal) FFS成年受益人,数据为6年(2004年9月1日至2010年8月31日)。队列受益人至少患有四种慢性疾病中的一种,包括哮喘、慢性阻塞性肺疾病(COPD)、糖尿病和心脏病。我们使用差异中差异(DiD)模型来评估生活在干预走廊(gmc, ngmc)的队列受益人的空气污染物浓度和医疗保健利用率(急诊室就诊和住院)是否比生活在ctrl的人群下降得更多。所有模型都控制了年龄、性别、语言、种族/民族、基线年合并症数量、县、时变健康指标变量和几个社区变量。为了便于解释,我们计算了政策干预后每三年的DiD估计值。DiD被用来评估管制政策对减少空气污染的因果影响,以及对健康结果的改善。我们通过使用多层次中介模型探讨了健康结果的改善是否由于空气污染的减少,其中转基因行动对健康结果的影响是通过政策实施后实际空气污染减少的影响来中介的。我们采用广义结构方程模型进行估算,并在模型中结合NO2和PM2.5的影响。为了进一步验证转基因行为对减少暴露和改善健康结果的因果关系,我们使用倾向评分加权进行了敏感性分析。结果:我们观察到,在所有10个县的参保者中,污染物NO2和PM2.5浓度都有统计学上的显著降低。从政策实施前到政策实施后,gmc参与者的二氧化氮和PM2.5的下降幅度大于控制区参与者。生活在ngmc中的受益人与生活在ctrl中的受益人相比,也观察到更大的减少,但这些减少比生活在gmc中的受益人要小。对于O3浓度,观察到相反的趋势。此外,我们观察到,在政策实施后的几年中,生活在gmc中的哮喘和COPD患者的急诊就诊次数明显高于生活在CTRLS中的患者。例如,我们在DiD模型结果中看到,如果认为CTRL组的区域趋势与GM政策无关,那么在gmc中,每年1000名哮喘受益人的急诊就诊次数减少了170次。 同样,在慢性阻塞性肺病受益人中,在实施该政策后的第三年,gmc估计每1000名患者的急诊就诊次数减少了180次。我们还观察到,当将ngmc与ctrl进行比较时,哮喘患者急诊室就诊的减少幅度更大,但减少幅度小于gmc与ctrl之间的比较。在政策实施后的一年中,慢性阻塞性肺病患者、糖尿病患者和ngmc中总样本的就诊次数也比对照组有下降趋势,但差异无统计学意义;当比较GMCs与ctrl和GMCs与NGMCs时,在糖尿病和心脏病患者中以及在总样本中也观察到类似的现象。虽然在政策实施后,gmc组的住院率比ngmc组下降更多,ngmc组的住院率比ctrl组下降更多,但结果没有统计学意义。使用中介模型,我们观察到,从政策实施前到政策实施后,每单位NO2和PM2.5的综合减少,哮喘患者的预期急诊室就诊次数减少0.129次(DiD = -0.129, P < 0.05)。中介模型估计的政策变化导致的NO2和PM2.5的减少与各自的DiD模型所显示的基本相同。中介分析表明,转基因政策干预对健康改善的影响主要是由于接触减少。最后,使用倾向得分的敏感性分析产生了类似的DiD结果。结论:本项目提供的经验证据表明,空气污染控制行动减少了弱势群体和易感人群的污染暴露。更重要的是,我们的研究结果表明,空气污染的减少导致了低收入慢性病患者健康状况的改善。我们的调查还为评估长期、大规模和复杂的监管行动对健康的影响提供了科学方法,这些行动包括常规收集的污染物和医疗索赔数据。因此,研究结果有力地支持了为全体社会成员改善空气质量的短期和长期努力,以及对空气污染控制政策影响的未来研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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