Research square

The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells.

Pub Date : 2025-01-07 DOI: 10.21203/rs.3.rs-4390765/v1 Jun Yang, Jie Fang, Shivendra Singh, Brennan Wells, Qiong Wu, Hongjian Jin, Laura Janke, Shibiao Wan, Jacob Steele, Jon Connelly, Andrew Murphy, Ruoning Wang, Andrew Davidoff, Margaret Ashcroft, Shondra Pruett-Miller

Integrative Analysis of Differentially Expressed Genes in Time-Course Multi-Omics Data with MINT-DE.

Pub Date : 2024-12-23 DOI: 10.21203/rs.3.rs-3806701/v1 Hao Xue, Sofie Y N Delbare, Martin T Wells, Sumanta Basu, Andrew G Clark

Long non-coding RNA Malat1 fine-tunes bone homeostasis and repair by orchestrating cellular crosstalk and the β-catenin-OPG/Jagged1 pathway.

Pub Date : 2024-10-11 DOI: 10.21203/rs.3.rs-3793919/v3 Yongli Qin, Jumpei Shirakawa, Cheng Xu, Ruge Chen, Xu Yang, Courtney Ng, Shinichi Nakano, Mahmoud Elguindy, Zhonghao Deng, Kannanganattu V Prasanth, Moritz F Eissmann, Shinichi Nakagawa, William M Ricci, Baohong Zhao