Biochimica et biophysica acta. Molecular basis of disease

Pathological forms of TDP-43 in amyotrophic lateral sclerosis (ALS) promote aberrant telomere elongation.

Pub Date : 2025-05-14 DOI: 10.1016/j.bbadis.2025.167906 Anna Konopka, Md Shafi Jamali, Megan Fowler, Prachi Mehta, Sonam Parakh, Zeinab Takalloo, Fabiha Farzana, Naima Mumtaz, Julie Hunter, Sina Shadfar, Mary-Louise Rogers, Julie D Atkin

Novel LBR pathogenic variants with loss of sterol reductase activity participate in the pathogenesis of skeletal dysplasia via dysregulating canonical Wnt pathway.

Pub Date : 2025-05-10 DOI: 10.1016/j.bbadis.2025.167901 Yilin Chen, Ying Bai, Dan Deng, Yiheng Liu, Linyang He, Mengru Wang, Mengchen Zhou, Xiangyi Wang, Chenguang Yu, Yue Wang, Feifei Zhao, Chengying Hai, Bo Wang, Junyi Liu, Xiangdong Kong, Xin Tu, Hui Li

Corrigendum to "CXCL12 derived from CD248-expressing cancer-associated fibroblasts mediates M2-polarized macrophages to promote nonsmall cell lung cancer progression" [Biochim. Biophys. Acta Mol. Basis Dis., 1868 (2022) 166521-166521/10.1016/j.bbadis.2022.166521].

Pub Date : 2025-04-26 DOI: 10.1016/j.bbadis.2025.167864 Jieheng Wu, Xinlei Liu, Jiangwei Wu, Chunju Lou, Qiaoling Zhang, Huiping Chen, Zeyang Yang, Shiqi Long, Yun Wang, Zhenling Shang, Zuquan Hu, Rui Zhang, Jian Zhang, Zhu Zeng