Anti-cancer drug design

Synthesis and anticancer activity of nordihydroguaiaretic acid (NDGA) and analogues.

Pub Date : 2001-12-01 R W McDonald, W Bunjobpon, T Liu, S Fessler, O E Pardo, I K Freer, M Glaser, M J Seckl, D J Robins

The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?

Pub Date : 2001-12-01 A McCluskey, S P Ackland, E Gardiner, C C Walkom, J A Sakoff

Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines.

Pub Date : 2001-12-01 L Rothenborg-Jensen, H F Hansen, I Wessel, J L Nitiss, G Schmidt, P B Jensen, M Sehested, L H Jensen