eGastroenterology

Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR.

Pub Date : 2025-09-30 DOI: 10.1136/egastro-2025-100227 Zakiyah R Henry, Syeda Maliha, Veronia Basaly, Zhenning Yang, Rulaiha E Taylor, Katherine Otersen, Vik Meadows, Daniel Rizzolo, Mary Stofan, Anisha Bhattacharya, Peihong Zhou, Anita Brinker, Ill Yang, Lanjing Zhang, Laurie B Joseph, Brian Buckley, Bo Kong, Grace L Guo

Mucosal DNA and RNA virome alterations and their interactions with human RNA and microRNA transcriptomes in colorectal polyps.

Pub Date : 2025-09-15 DOI: 10.1136/egastro-2025-100194 Siu Hei Shoshanna So, Wei Jiang, Yingshi Li, Georgina L Hold, Kathleen Goodrick, Ahyeon Min, Michael J Bourke, Emad M El-Omar, Xiao-Tao Jiang, Howard Chi Ho Yim

Gut dysbiosis is linked to severe steatosis and enhances its diagnostic performance in MASLD.

Pub Date : 2025-08-24 DOI: 10.1136/egastro-2025-100204 Marta Borges-Canha, Javier Centelles-Lodeiro, Ana Rita Leite, Joana Chaves, Inês Mariana Lourenço, Madalena Von-Hafe, Catarina Vale, Diana Martins, Cláudia Silva, António Carlos Ferreira, Gwen Falony, Rodrigo Liberal, Mariana Fragão-Marques, António Barros, Isabel Miranda, Adelino Leite-Moreira, Pedro Pimentel-Nunes, Sara Vieira-Silva, João Sérgio Neves