Discovery immunology

Human and porcine IgG subclasses differentially engage porcine Fc receptors.

Pub Date : 2026-09-21 DOI: 10.1093/discim/kyag018 Ashutosh Vats, Charlotte May, Elliot Moorhouse, Elena Lokhman, Sylvia Crossley, Abigail Hay, Marie Bonnet-Di Placido, Simon P Graham, Pramila Rijal, Alain Townsend, William Mwangi, John C Schwartz, Danish Munir, John A Hammond, Elma Tchilian, Basudev Paudyal

Gut irradiation and microbiota status modulate the meningeal immune landscape.

Pub Date : 2026-09-18 DOI: 10.1093/discim/kyag019 Clara H Whiteley, Urszula M Cytlak, Isobelle L Blair, Samuel J Ashman, Helen Parker, Timothy M Illidge, Douglas P Dyer, Mark A Travis, Andrew D Greenhalgh

E. coli O157:H7 evades CD8⁺ T cell immunity through T3SS-dependent suppression and limited MHCI presentation of translocated proteins.

Pub Date : 2026-09-09 DOI: 10.1093/discim/kyag017 Amany Hassan, Annalisa Nicastri, Deepali Vasoya, Joana Alves, Morten Nielsen, David L Gally, Nicola Ternette, Alexander Corbishley, Timothy K Connelley