Molecular neurodegeneration advances

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Molecular neurodegeneration advances - 最新文献

Uncovering plaque-glia niches in human Alzheimer's disease brains using spatial transcriptomics.

Pub Date : 2025-01-01 DOI: 10.1186/s44477-025-00002-z Denis R Avey, Bernard Ng, Ricardo A Vialle, Nicola A Kearns, Katia de Paiva Lopes, Artemis Iatrou, Sashini De Tissera, Himanshu Vyas, Devin M Saunders, Daniel J Flood, Jishu Xu, Shinya Tasaki, Chris Gaiteri, David A Bennett, Yanling Wang

Dose-ranging and further therapeutic evaluation of a bicistronic humanized TrkB-BDNF gene therapy for glaucoma in rodents.

Pub Date : 2025-01-01 DOI: 10.1186/s44477-025-00003-y Andrew Osborne, Tasneem Z Khatib, Michael Whitehead, Terrance Mensah, Sadat Yazdouni, Bart Nieuwenhuis, Zara Ali, Jared Ching, Robert Watt, Naoki Kishi, Naoki Kozono, James R Tribble, Peter S Widdowson, Keith R Martin

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