The Journal of Clinical Investigation

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The Journal of Clinical Investigation - 最新文献

Pulmonary fibroblast-derived stem cell factor promotes neutrophilic asthma by augmenting IL-17A production from ILC3s.

Pub Date : 2025-07-17 DOI: 10.1172/jci187372 Jheng-Syuan Shao,Alan C Lai,Wei-Chang Huang,Ko-Chien Wu,Po-Yu Chi,Yao-Ming Chang,Ya-Jen Chang

Endocochlear potential contributes to hair cell death in TMPRSS3 hearing loss.

Pub Date : 2025-07-17 DOI: 10.1172/jci186395 A Eliot Shearer,Yuan-Siao Chen,Stephanie L Rouse,Xiaohan Wang,Janmaris Marin Fermin,Kevin Ta Booth,Jasmine Moawad,Nicole Bianca Libiran,Jinan Li,Hae-Young Kim,Michael Hoa,Rafal Olszewski,Jing-Yu Lei,Ernesto Cabrera,Douglas J Totten,Bo Zhao,Jeffrey R Holt,Rick F Nelson

Chemokine gradients spare graft endothelium from CD8+ T cell-mediated injury during allograft rejection.

Pub Date : 2025-07-15 DOI: 10.1172/jci193454 Scott M Krummey,Jonathan S Bromberg

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