The EMBO Journal

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The EMBO Journal - 最新文献

SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.

Pub Date : 2025-01-29 DOI: 10.1038/s44318-025-00369-5 Wei Li,Jing Han,Bin Huang,Tengteng Xu,Yihong Wan,Dan Luo,Weiyao Kong,Ying Yu,Lei Zhang,Yong Nian,Bo Chu,Chengqian Yin

Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis.

Pub Date : 2025-01-28 DOI: 10.1038/s44318-024-00359-z Yan Huang,Hua Lu,Yao Liu,Jiabei Wang,Qingan Xia,Xiangmin Shi,Yan Jin,Xiaolin Liang,Wei Wang,Xiaopeng Ma,Yangyi Wang,Meng Gong,Canjun Li,Chunlei Cang,Qinghua Cui,Ceshi Chen,Tao Shen,Lianxin Liu,Xiangting Wang

Structural basis for human NKCC1 inhibition by loop diuretic drugs.

Pub Date : 2025-01-28 DOI: 10.1038/s44318-025-00368-6 Yongxiang Zhao,Pietro Vidossich,Biff Forbush,Junfeng Ma,Jesse Rinehart,Marco De Vivo,Erhu Cao

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