The Journal of clinical investigation

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The Journal of clinical investigation - 最新文献

STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma

Pub Date : 2024-06-17 DOI: 10.1172/jci175033 Hinda Najem, S. Lea, Shashwat Tripathi, Lisa Hurley, Chao-Hsien Chen, Ivana William, Moloud Sooreshjani, Michelle Bowie, Genevieve Hartley, Corey Dussold, Sebastian Pacheco, C. Dmello, Catalina Lee-Chang, Kathleen McCortney, Alicia Steffens, Jordain Walshon, Martina Ott, Jun Wei, Anantha L. Marisetty, I. Balyasnikova, R. Stupp, R. Lukas, Jian Hu, C. D. James, C. Horbinski, Maciej S. Lesniak, David M. Ashley, Waldemar Priebe, Leonidas C. Platanias, Michael A. Curran, Amy B. Heimberger

Mutations in the cytoplasmic iron-sulfur assembly protein CIAO1 cause neuromuscular deficits

Pub Date : 2024-06-17 DOI: 10.1172/jci182474 P. Opal

Dicarboxylic acids counteract the metabolic effects of a Western diet by boosting energy expenditure

Pub Date : 2024-06-17 DOI: 10.1172/JCI181978 L. Castagneto-Gissey, Stefan R. Bornstein, G. Mingrone

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