A109. MICE TO HUMANS: MECHANISTIC DISCOVERIES IN SLEEP APNEA

Effects of HIF-1α Inhibition on the Metabolic Effects of Intermittent Hypoxia in a Rodent Model of Diabetes Mellitus

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2716 U. Magalang, J. Poblete, T. Eubank, S. Bao

Obstructive Sleep Apnea (OSA)-related Intermittent Hypoxia (IH) Induces Hepatic Senescence in a Mouse Model

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2717 Y. Wang, S. Deng, Y. Chen, J. Kuang, X. Xiao, Y. Li

Senolytic Treatment Combined With Reduction of Intermittent Hypoxia (IH) Exposure Duration Mimicking "Good" CPAP Adherence Improves Coronary Artery Function in a Murine Model of OSA

Pub Date : 2023-05-01 DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2711 M. Badran, C. Puech, A. Khalyfa, D. Gozal