Blood Cancer Discovery

The journal Blood Cancer Discovery publishes high-quality Research Articles and Briefs that focus on major advances in basic, translational, and clinical research of leukemia, lymphoma, myeloma, and associated diseases. The topics covered include molecular and cellular features of pathogenesis, therapy response and relapse, transcriptional circuits, stem cells, differentiation, microenvironment, metabolism, immunity, mutagenesis, and clonal evolution. These subjects are investigated in both animal disease models and high-dimensional clinical data landscapes. The journal also welcomes submissions on new pharmacological, biological, and living cell therapies, as well as new diagnostic tools. They are interested in prognostic, diagnostic, and pharmacodynamic biomarkers, and computational and machine learning approaches to personalized medicine. The scope of submissions ranges from preclinical proof of concept to clinical trials and real-world evidence. Blood Cancer Discovery serves as a forum for diverse ideas that shape future research directions in hematooncology. In addition to Research Articles and Briefs, the journal also publishes Reviews, Perspectives, and Commentaries on topics of broad interest in the field.

《Blood Cancer Discovery》是美国癌症研究学会(AACR)于2020年创立的新刊物。期刊发布高质量的研究论文和简报，着重关注白血病、淋巴瘤、骨髓瘤等相关疾病的基础、转化和临床研究的重大进展。其涵盖的主题包括疾病发病机制的分子和细胞特征、治疗反应和复发、转录调控、干细胞、分化、微环境、代谢、免疫、诱变和克隆进化等方面。这些研究主题在动物模型和临床数据等高维数据领域得到深入探讨。 此外，该期刊鼓励提交新的药理学、生物学和活细胞治疗方法，以及新的诊断工具。他们对预后、诊断、药效生物标志物以及个性化医疗中的计算和机器学习方法也表现出浓厚兴趣。投稿范围从临床前概念验证到临床试验和实际应用等各个阶段。 《Blood Cancer Discovery》是一个讨论塑造血液肿瘤学未来研究方向的平台。除了研究论文和简报外，该期刊还发表了有关该领域其他感兴趣主题的评论、观点和评论文章。