The Journal of Pharmacology and Experimental Therapeutics

Drug-Drug Interactions of Antidepressant Ammoxetine Mediated by CYP2D6 and MATE1: From In Vitro Mechanistic Investigations to In Vivo Validation

Pub Date : 2026-03-01 DOI: 10.1016/j.jpet.2026.104312 Juanwen Hu, Zhihui Liu, Qiannan Zhang, Cong Li, Xia Wu, Wenpeng Zhang, Youzhi Zhang, Xiaomei Zhuang

The CaMKII Inhibitory Peptide AIP Alleviates Renal Fibrosis Through the TGF-β/Smad and RAF/ERK Pathways

Pub Date : 2023-07-07 DOI: 10.2139/ssrn.4280191 Xiaocui Feng, Jianfeng Zhang, R. Yang, Jingya Bai, Bochuan Deng, Lu Cheng, Feiyun Gao, Junqiu Xie, Bang-zhi Zhang

Deconvolution of Plasma Pharmacokinetics from Dynamic Heart Imaging Data Obtained by Single Positron Emission Computed Tomography/Computed Tomography Imaging

Pub Date : 2022-11-18 DOI: 10.1101/2022.11.17.517003 Zengtao Wang, Lushan Wang, Malik Ebbini, G. Curran, Paul H. Min, Ronald A. Siegel, V. J. Lowe, K. Kandimalla