C28. PATHWAYS OF LUNG MORPHOGENESIS

Kruppel-Like Factor 4 (Klf4) Is a Novel Regulator of Forkhead Box Protein O1 (FOXO1) and of Neonatal Lung Fibroblast Function and Reduced in Hyperoxia-Induced Lung Injury

Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4444 D. Hirani, M. Koch, J. Mohr, Katharina Dinger, C. Vohlen, Christian Klaudt, J. Dötsch, M. A. Alcázar

Single-Cell Transcriptomic Analysis of Type 2 Alveolar Epithelial Cell Differentiation from Induced Pluripotent Stem Cells: An Emerging Tool to Model Interstitial Lung Diseases

Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4445 K. Hurley, Anjali Jacob, Jun Ding, C. Lin, F. Hawkins, C. Villacorta-Martin, Z. Bar-Joseph, D. Kotton

Type 2 Cell Low Density Lipoprotein Receptor Related Protein 1 (LRP1) Regulates Surfactant Homeostasis

Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4448 Christina W. Agudelo, S. Mendizuri, E. Area-Gomez, Yimeng Xu, P. Geraghty, I. Goldberg, R. Foronjy, I. Garcia-Arcos