medRxiv : the preprint server for health sciences

Neuroimaging-AI endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders.

Pub Date : 2025-03-28 DOI: 10.1101/2023.08.16.23294179 Junhao Wen, Ioanna Skampardoni, Ye Ella Tian, Zhijian Yang, Yuhan Cui, Guray Erus, Gyujoon Hwang, Erdem Varol, Aleix Boquet-Pujadas, Ganesh B Chand, Ilya Nasrallah, Theodore D Satterthwaite, Haochang Shou, Li Shen, Arthur W Toga, Andrew Zalesky, Christos Davatzikos

Nigral volume loss in prodromal, early, and moderate Parkinson's disease.

Pub Date : 2025-03-21 DOI: 10.1101/2023.08.19.23294281 Jason Langley, Kristy S Hwang, Daniel E Huddleston, Xiaoping P Hu

Pharmacokinetic effects of a single-dose nutritional ketone ester supplement on brain glucose and ketone metabolism in alcohol use disorder.

Pub Date : 2025-03-03 DOI: 10.1101/2023.09.25.23296090 Xinyi Li, Anthony J Young, Zhenhao Shi, Juliana Byanyima, Sianneh Vesslee, Rishika Reddy, Timothy Pond, Mark Elliott, Ravinder Reddy, Robert K Doot, Jan-Willem van der Veen, Henry R Kranzler, Ravi Prakash Reddy Nanga, Jacob G Dubroff, Corinde E Wiers